Tanaka Atsuo, Mihara Futoshi, Yoshiura Takashi, Togao Osamu, Kuwabara Yasuo, Natori Yoshihiro, Sasaki Tomio, Honda Hiroshi
Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka 812-8582, Japan.
AJR Am J Roentgenol. 2004 Dec;183(6):1799-804. doi: 10.2214/ajr.183.6.01831799.
The purpose of this study was to determine the capability of dynamic contrast MRI to differentiate hemangioma from schwannoma of the orbit.
Sixteen patients (three males and 13 females; mean age, 39 +/- 17.3 [SD] years; age range, 10-71 years) with unilateral orbital tumors, including eight cavernous hemangiomas and eight schwannomas, were examined. In addition to conventional MRI, we performed a dynamic contrast study (fast spin-echo sequence, 20-sec interval) after bolus administration of the contrast material (gadopentetate dimeglumine, 0.1 mmol/kg). We evaluated the features of the contrast enhancement spread pattern and the tumors' time-intensity curves.
In the early phase, all the hemangiomas started the enhancement from one point or portion, although all the schwannomas started the enhancement from a wide area. The difference in the contrast-enhancement spread pattern features between the two types of tumors was statistically significant (p < 0.0001). The gradient of the time-intensity curve did not show a significant difference.
Hemangioma and schwannoma of the orbit can be differentiated by the contrast-enhancement spread pattern on dynamic MRI.
本研究的目的是确定动态对比增强磁共振成像（MRI）区分眼眶血管瘤与神经鞘瘤的能力。
对16例单侧眼眶肿瘤患者（3例男性，13例女性；平均年龄39±17.3[标准差]岁；年龄范围10 - 71岁）进行检查，其中包括8例海绵状血管瘤和8例神经鞘瘤。除常规MRI外，在静脉推注对比剂（钆喷酸葡胺，0.1 mmol/kg）后，我们进行了动态对比研究（快速自旋回波序列，间隔20秒）。我们评估了对比增强扩散模式的特征和肿瘤的时间 - 强度曲线。
在早期阶段，所有血管瘤均从一点或一部分开始增强，而所有神经鞘瘤均从广泛区域开始增强。两种类型肿瘤之间对比增强扩散模式特征的差异具有统计学意义（p < 0.0001）。时间 - 强度曲线的斜率未显示出显著差异。
眼眶血管瘤和神经鞘瘤可通过动态MRI上的对比增强扩散模式进行区分。
