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一例罕见的创伤后头痛合并颅内低压病例。

An Unusual Case of Post-Traumatic Headache Complicated by Intracranial Hypotension.

作者信息

Siavoshi Sara, Dougherty Carrie, Ailani Jessica, Yadwadkar Kaustubh, Berkowitz Frank

机构信息

Department of Neurology, Georgetown University Hospital, Washington, DC 20007, USA.

出版信息

Brain Sci. 2016 Dec 29;7(1):3. doi: 10.3390/brainsci7010003.

DOI:10.3390/brainsci7010003
PMID:28036062
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5297292/
Abstract

We present a case of post-traumatic headache complicated by intracranial hypotension resulting in an acquired Chiari malformation and myelopathy with syringomyelia. This constellation of findings suggest a possible series of events that started with a traumatic cerebral spinal fluid (CSF) leak, followed by descent of the cerebellar tonsils and disruption of CSF circulation that caused spinal cord swelling and syrinx. This unusual presentation of post-traumatic headache highlights the varying presentations and the potential sequelae of intracranial hypotension. In addition, the delayed onset of upper motor neuron symptoms along with initially normal head computerized tomography scan (CT) findings, beg the question of whether or not a post-traumatic headache warrants earlier magnetic resonance imaging (MRI).

摘要

我们报告一例创伤后头痛合并颅内低压,导致获得性小脑扁桃体下疝畸形及脊髓空洞症伴脊髓病。这一系列的发现提示了可能的事件顺序,始于创伤性脑脊液漏,随后小脑扁桃体下移及脑脊液循环中断,进而导致脊髓肿胀和空洞形成。创伤后头痛的这种不寻常表现突出了颅内低压的不同表现形式及其潜在后遗症。此外,上运动神经元症状的延迟出现以及最初头部计算机断层扫描(CT)结果正常,引发了关于创伤后头痛是否需要更早进行磁共振成像(MRI)检查的问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32e0/5297292/0b493098eb35/brainsci-07-00003-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32e0/5297292/2539199f15fd/brainsci-07-00003-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32e0/5297292/9dd3d3c4de6c/brainsci-07-00003-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32e0/5297292/0b493098eb35/brainsci-07-00003-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32e0/5297292/2539199f15fd/brainsci-07-00003-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32e0/5297292/9dd3d3c4de6c/brainsci-07-00003-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32e0/5297292/0b493098eb35/brainsci-07-00003-g003.jpg

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本文引用的文献

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Spontaneous low pressure, low CSF volume headaches: spontaneous CSF leaks.自发性低颅压、低脑脊髓液体积头痛:自发性脑脊髓液漏。
Headache. 2013 Jul-Aug;53(7):1034-53. doi: 10.1111/head.12149. Epub 2013 Jun 28.
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Post-traumatic syringomyelia.创伤后脊髓空洞症
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On a Case of Concussion-Lesion, with extensive secondary degenerations of the Spinal Cord, followed by General Muscular Atrophy.关于一例脑震荡损伤病例,伴有脊髓广泛继发性变性,随后出现全身肌肉萎缩。
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Post-traumatic syringomyelia: a review of the cases presenting in a regional spinal injuries unit in the north east of England over a 5-year period.创伤后脊髓空洞症:对英格兰东北部一个地区性脊柱损伤治疗中心5年内收治病例的回顾。
Spine (Phila Pa 1976). 2005 May 15;30(10):1206-10. doi: 10.1097/01.brs.0000162277.76012.0b.
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Spontaneous low cerebrospinal pressure: a mini review.自发性低脑脊液压力:一篇小型综述。
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Acute foramen magnum syndrome caused by an acquired Chiari malformation after lumbar drainage of cerebrospinal fluid: report of three cases.脑脊液腰椎引流后获得性Chiari畸形所致急性枕大孔综合征:三例报告
Neurosurgery. 2002 Sep;51(3):823-8; discussion 828-9.
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Spontaneous CSF leaks: underlying disorder of connective tissue.自发性脑脊液漏:结缔组织的潜在疾病。
Neurology. 2002 Mar 12;58(5):814-6. doi: 10.1212/wnl.58.5.814.
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Elucidating the pathophysiology of syringomyelia.阐明脊髓空洞症的病理生理学。
J Neurosurg. 1999 Oct;91(4):553-62. doi: 10.3171/jns.1999.91.4.0553.