Meineri P, Torre E, Rota E, Grasso E
Department of Neurology, ASO S. Croce e Carle, Via Coppino 26, I-12100 Cuneo, Italy.
Neurol Sci. 2004 Oct;25 Suppl 3:S281-2. doi: 10.1007/s10072-004-0310-8.
We present a retrospective clinical study of 18 cases of new daily persistent headache (NDPH), a rare chronic headache, included in the fourth chapter of the II IHS classification; the pathophysiology of NDPH is unknown but a link with viral infections (especially Epstein-Barr virus (EBV)) has been suggested. Comparing our series with the other two published until now, we did not find any particular difference, as regards to clinical aspects. However, our laboratory tests show a recent herpes simplex virus infection in 42% and cytomegalovirus in 11% of cases; moreover we could not find any EBV infection. Our data suggest that viruses other than EBV can play a role in NDPH.
我们对18例新发性每日持续性头痛（NDPH）进行了一项回顾性临床研究，NDPH是一种罕见的慢性头痛，被纳入国际头痛协会（IHS）分类第三章的第四章；NDPH的病理生理学尚不清楚，但有人提出它与病毒感染（尤其是EB病毒（EBV））有关。将我们的系列病例与目前已发表的其他两个系列进行比较，在临床方面我们未发现任何特别差异。然而，我们的实验室检测显示，42%的病例近期有单纯疱疹病毒感染，11%的病例有巨细胞病毒感染；此外，我们未发现任何EBV感染。我们的数据表明，除EBV外的其他病毒可能在NDPH中起作用。
