Harper C M, Ambler G, Edge G
Brighton and Sussex University Hospitals, UK.
Anaesthesia. 2004 Dec;59(12):1160-2. doi: 10.1111/j.1365-2044.2004.03940.x.
The majority of patients with Duchenne's muscular dystrophy require corrective spinal surgery for scoliosis to maintain seated balance and to slow the progression of respiratory compromise, thereby facilitating nursing and enhancing their quality of life. Traditionally patients with a pre-operative forced vital capacity (PFVC) of 30% or below predicted have been denied this surgery as it was thought that the incidence of postoperative complications was unacceptably high. We present data collected prospectively from 45 consecutive operations undertaken in our unit. These cases indicate that there is no clinically significant difference in operative and postoperative outcomes between patients with PFVC > 30% and < or =30%. However, the routine postoperative use of mask ventilation to facilitate early tracheal extubation is vital.
大多数杜氏肌营养不良症患者需要进行脊柱侧弯矫正手术,以维持坐姿平衡并减缓呼吸功能损害的进展,从而便于护理并提高生活质量。传统上,术前用力肺活量(PFVC)低于预测值30%的患者被拒绝进行该手术,因为人们认为术后并发症的发生率高得难以接受。我们展示了从我们科室连续进行的45例手术中前瞻性收集的数据。这些病例表明,PFVC>30%和≤30%的患者在手术及术后结果方面没有临床显著差异。然而,术后常规使用面罩通气以促进早期气管拔管至关重要。