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杜氏脊柱侧凸的远端融合:术前骨盆倾斜的相关性。一项病例系列研究。

Distal fusion in Duchenne scoliosis: the relevance of preoperative pelvic obliquity. A case series study.

机构信息

Orthopaedic and Spine Department, Great Ormond Street Hospital, London, WC1N 3JH, UK.

Division of Neurosurgery, St Michael's Hospital, University of Toronto, Toronto, Canada.

出版信息

Spine Deform. 2023 Sep;11(5):1261-1270. doi: 10.1007/s43390-023-00689-8. Epub 2023 Jun 7.

Abstract

PURPOSE

The aim of this study was to determine clinical and radiographic outcomes for Duchenne Muscular Dystrophy (DMD) patients who underwent posterior spinal fusion from T2/3 to L5 (without pelvic fixation), at this single centre.

METHODS

From January 2012 to January 2020, 29 consecutive DMD scoliosis patients underwent posterior spinal fusion using pedicle screws from T2/3 to L5 in a single center with a minimum of 3 years follow-up (FU). Radiologic measurements and chart review were performed.

RESULTS

Twenty nine patients aged 14 ± 1.5 years were included. No patient was lost to FU. All patients had significant correction in Cobb angle, pelvic obliquity (PO) and lumbar lordosis (LL), without loss of correction at last FU. The mean values for preoperative, immediate postoperative and last FU were CA 62o, 15o and 17o, PO: 21o, 8o and 9o; and LL 10o, -41o and -41o respectively. Correction in CA was independent of any variable analysed including implant density, rod diameter, traction, or bone density. Regarding PO, it was inversely related to age and independent of all other variables. Factors associated with postoperative complications were age and respiratory function.

CONCLUSIONS

It appears from our results that pelvic fixation might not always be required in DMD scoliosis surgery, when using pedicle screws with lowest instrumented vertebra at L5. However, larger preoperative PO values can be related with residual PO. It seems that probably related to the underlying condition, early surgery may decrease incidence of complications.

LEVEL OF EVIDENCE

IV.

摘要

目的

本研究旨在确定在单一中心接受 T2/3 至 L5(不包括骨盆固定)后路脊柱融合术的杜氏肌营养不良症(DMD)患者的临床和影像学结果。

方法

2012 年 1 月至 2020 年 1 月,29 例 DMD 脊柱侧凸患者在单一中心接受 T2/3 至 L5 的后路脊柱融合术,均使用椎弓根螺钉,随访时间至少为 3 年(FU)。进行放射学测量和图表审查。

结果

29 例年龄为 14±1.5 岁的患者被纳入研究。无患者失访。所有患者 Cobb 角、骨盆倾斜度(PO)和腰椎前凸(LL)均有显著矫正,末次 FU 时无矫正丢失。术前、即刻术后和末次 FU 的平均 Cobb 角分别为 62o、15o 和 17o,PO 分别为 21o、8o 和 9o;LL 分别为 10o、-41o 和-41o。Cobb 角的矫正与分析的任何变量无关,包括植入物密度、杆直径、牵引或骨密度。关于 PO,它与年龄呈负相关,与所有其他变量无关。术后并发症的相关因素是年龄和呼吸功能。

结论

从我们的结果来看,当使用最低固定椎为 L5 的椎弓根螺钉时,DMD 脊柱侧凸手术可能不一定需要骨盆固定。然而,较大的术前 PO 值可能与残留的 PO 相关。似乎与潜在疾病有关,早期手术可能会降低并发症的发生率。

证据水平

IV。

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