Bukulmez Orhan, Arici Aydin
Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, The University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390-9032, USA.
Obstet Gynecol Clin North Am. 2004 Dec;31(4):727-44, ix. doi: 10.1016/j.ogc.2004.08.007.
Although the diagnosis of luteal phase defect (LPD) has been described convincingly in the research setting, it remains a controversial clinical entity. Apart from many uncertainties that surround the diagnosis of LPD, there is no convincing evidence that LPD is associated with infertility and recurrent abortion. Once diagnosed, the treatment options are empiric and include those that are recommended for unexplained infertility. The efforts to diagnose LPD in patients who have infertility or recurrent abortion are not justified.
尽管黄体期缺陷（LPD）的诊断在研究环境中已有令人信服的描述，但它仍是一个存在争议的临床实体。除了围绕LPD诊断的诸多不确定性外，没有令人信服的证据表明LPD与不孕和反复流产有关。一旦确诊，治疗方案是经验性的，包括那些针对不明原因不孕推荐的方案。对不孕或反复流产患者进行LPD诊断的努力是不合理的。
