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髋关节恶性病理性骨折治疗失败后关节置换术的并发症及结果

Complications and results of arthroplasty for salvage of failed treatment of malignant pathologic fractures of the hip.

作者信息

Jacofsky David J, Haidukewych George J, Zhang Heyu, Sim Franklin H

机构信息

Mayo Clinic, Rochester, MN 55905, USA.

出版信息

Clin Orthop Relat Res. 2004 Oct(427):52-6. doi: 10.1097/01.blo.0000143572.96021.93.

Abstract

The purpose of this study was to evaluate the results and complications of hip arthroplasty done for salvage of failed treatment of pathologic proximal femoral fractures secondary to malignancy. Between 1980 and 2000, 42 patients with a mean age of 63 years were treated with hip arthroplasty to salvage failed treatment of a pathologic proximal femoral fracture. Total hip arthroplasty was done in 16 patients (3 uncemented, 2 hybrid, 11 cemented), and bipolar hemiarthroplasty in 26 (2 uncemented, 24 cemented). A modular, proximal femoral replacement construct was used in 15 patients. Patients were followed a mean of 5.8 years (range, 15 days-20 years). Four hips required reoperation, all for deep infection. Harris Hip score improved from an average of 42 points (range, 17-76 points) preoperatively to an average of 83 points (range, 52-100 points) postoperatively. Most recent radiographs showed femoral component loosening in only one patient. Implant survivorship free of revision for any reason at 5 years was 90% (range, 65-96%) and free of revision for aseptic failure or radiographic failure was 97% (range, 64-99%). Hip arthroplasty is an effective treatment for salvage of failed treatment of pathologic proximal femoral fractures. Modular proximal femoral replacements were often required. The most concerning complication was deep prosthetic infection, which occurred in nearly 10% of this patient population, and in 21% of patients with prior irradiation.

摘要

本研究的目的是评估为挽救继发于恶性肿瘤的病理性股骨近端骨折治疗失败而行髋关节置换术的结果及并发症。1980年至2000年间,42例平均年龄63岁的患者接受了髋关节置换术,以挽救病理性股骨近端骨折治疗失败的情况。16例患者行全髋关节置换术(3例非骨水泥型,2例混合型,11例骨水泥型),26例患者行双极半髋关节置换术(2例非骨水泥型,24例骨水泥型)。15例患者使用了模块化股骨近端置换假体。患者平均随访5.8年(范围15天至20年)。4例髋关节需要再次手术,均因深部感染。Harris髋关节评分从术前平均42分(范围17 - 76分)提高到术后平均83分(范围52 - 100分)。最近的X线片显示仅1例患者股骨假体松动。5年时因任何原因无需翻修的假体生存率为90%(范围65% - 96%),因无菌性失败或影像学失败无需翻修的生存率为97%(范围64% - 99%)。髋关节置换术是挽救病理性股骨近端骨折治疗失败的有效方法。常需要使用模块化股骨近端置换假体。最令人担忧的并发症是深部假体感染,在近10%的该患者群体中发生,在既往接受过放疗患者中发生率为21%。

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