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[鲟鱼(鲟科,鲟形目)血清蛋白抗原的年龄相关变异性]

[Age-related variability of serum protein antigens in sturgeons (Acipenseridae, Acipenseriformes)].

作者信息

Subbotkin M F, Subbotkina T A

出版信息

Ontogenez. 2004 Sep-Oct;35(5):360-6.

Abstract

We studied the variability of antigenic properties of proteins in two sturgeon species at different stages of postembryonic development. The deepest changes occurred in individual components of albumins and beta-globulins (transferrins) and were mostly related to an increased proportion of the protein accounting for these antigens. Transformation of the main component of albumins A1 into adult antigens was completed in 5-month old fry. The main component of beta-globulins A (component of transferrins) appeared in the blood flow much later than other proteins and could retain the fry features until the age of 3-4 years. Other antigens belonging to alpha1- and alpha2-globulins and the second component of transferrins were more stable and did not undergo substantial changes. The direction of ontogenetic variability of serum antigens in sturgeon fry did not depend on the habitat of adult fish in fresh or sea water.

摘要

我们研究了两种鲟鱼在胚后发育不同阶段蛋白质抗原特性的变异性。最深层次的变化发生在白蛋白和β-球蛋白(转铁蛋白)的各个组分中,且主要与占这些抗原的蛋白质比例增加有关。白蛋白A1的主要成分向成年抗原的转变在5月龄鱼苗中完成。β-球蛋白A(转铁蛋白的组分)的主要成分在血流中出现的时间比其他蛋白质晚得多,并且在3 - 4岁之前可能保留鱼苗特征。属于α1-和α2-球蛋白以及转铁蛋白第二组分的其他抗原更稳定,未发生实质性变化。鲟鱼苗血清抗原个体发育变异性的方向不取决于成年鱼在淡水或海水中的栖息地。

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