[猪胚胎血清蛋白的免疫电泳研究]
[Immunoelectrophoretic study of serum proteins of swine embryos].
作者信息
Aleshko S F, Ermishin A P, Savenok G A, Krachkovskaia A N
出版信息
Zh Evol Biokhim Fiziol. 1977 Mar-Apr;13(2):152-6.
During embryonic development, antigenic spectrum of serum proteins from porcine foetuses gradually become more complex, the number of antigens increasing from 4 in 1-month embryos to 12--13 in mature foetuses. Immunoelectrophoretic analysis of the serum reveals prealbumin, alpha- and beta-globulins. It was shown that with respect to its immunological properties, procine fetuin is not presented by a true stage-specific protein, since together with ESA-glogulin it contains antigens which are identical to those in the blood serum of adult animals. Immunoelectrophoresis did not reveal gamma-globulins in embryonic serum. It is suggested that porcine foetuses may synthesize the main proteins of the blood serum; however, final formation of antigenic spectrum is accomplished in postembryonic period.
在胚胎发育过程中，猪胎儿血清蛋白的抗原谱逐渐变得更加复杂，抗原数量从1月龄胚胎中的4种增加到成熟胎儿中的12 - 13种。血清的免疫电泳分析显示有前白蛋白、α-球蛋白和β-球蛋白。结果表明，就其免疫特性而言，猪胎球蛋白并非真正的阶段特异性蛋白，因为它与ESA-球蛋白一起含有与成年动物血清中相同的抗原。免疫电泳未在胚胎血清中发现γ-球蛋白。据推测，猪胎儿可能合成血清中的主要蛋白质；然而，抗原谱的最终形成是在胚胎后期完成的。
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