[一项关于社区居民高尿酸血症危险因素的社区病例对照研究]

[A community-based case-control study on risk factors of hyperuricemia among residents in the community].

作者信息

Shao Ji-Hong, Shen Hong-Bing, Mo Bao-Qing, Xu Yao-Chu

机构信息

Department of General Physiology, Xuzhou Medical College, Xuzhou 221002, China.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 2004 Aug;25(8):688-90.

PMID:15555393

Abstract

OBJECTIVE

To investigate the risk factors of hyperuricemia among residents aged >/= 20 years.

METHODS

A community based case-control study was conducted in 286 patients with 858 controls without hyperuricemia. Available data were analyzed by mono-factorial and multi-factorial logistic regression methods using SPSS 10.0 software.

RESULTS

17 factors related to exposure were identified for hyperuricemia the mono-factorial analysis when; five factors were selected through multiple factoral logistic regression model at P = 0.05 level. The risk factors on hyperuricemia were: hypertriglyceridemia (OR = 3.069), alcohol consumption (OR = 2.032), obesity (OR = 1.802), taste of spicy food (OR = 1.877) and hyperglycemia (OR = 1.622).

CONCLUSION

Hyperuricemia is a disease associated with environment and style-life. Changing lifestyle, such as decreasing alcohol consumption and adopting proper structure of diet may prevent or decrease the chance of getting hyperuricemia and gout.

摘要

目的

调查年龄≥20岁居民高尿酸血症的危险因素。

方法

对286例高尿酸血症患者和858例无高尿酸血症的对照者进行基于社区的病例对照研究。使用SPSS 10.0软件，通过单因素和多因素逻辑回归方法对可得数据进行分析。

结果

单因素分析确定了17个与高尿酸血症暴露相关的因素；通过多因素逻辑回归模型在P = 0.05水平筛选出5个因素。高尿酸血症的危险因素为：高甘油三酯血症（OR = 3.069）、饮酒（OR = 2.032）、肥胖（OR = 1.802）、喜食辛辣食物（OR = 1.877）和高血糖（OR = 1.622）。