Domán István, Illés Tamás
Department of Orthopaedic Surgery, Medical and Health Sciences Centre, University of Pécs, Szigeti ut 12, Pecs 7643, Hungary.
J Biochem Biophys Methods. 2004 Oct 29;61(1-2):207-14. doi: 10.1016/j.jbbm.2004.06.004.
Intervertebral disc (IVD) degeneration is one of the most common musculuskeletal disorders affecting western society. Degeneration alters the morphology and the mechanical properties of the discs. According to previous reports, DSC proved to be a suitable method for the demonstration of thermal consequences of local as well as global conformational changes in the structure of the human intervertebral discs. In the present study, a wide spectrum of degenerated IVD was examined by DSC. The results suggest that definitive differences exist between the stages of disc degeneration in calorimetric measures.
椎间盘（IVD）退变是影响西方社会的最常见肌肉骨骼疾病之一。退变会改变椎间盘的形态和力学性能。根据先前的报道，差示扫描量热法（DSC）被证明是一种适用于证明人类椎间盘结构中局部以及整体构象变化的热效应的方法。在本研究中，通过DSC检查了广泛的退变椎间盘。结果表明，在热分析测量中，椎间盘退变阶段之间存在明确差异。
