Lertsithichai Panuwat, Rattanapichart Pudsaporn
Department of Surgery, Ramathibodi Hospital Medical School, Mahidol University, Bangkok, Thailand.
Asian J Surg. 2004 Jul;27(3):202-10; discussion 211-2. doi: 10.1016/S1015-9584(09)60033-6.
To compare the complications of temporary diverting ileostomy with those of temporary colostomy for patients with colorectal diseases.
Two independent researchers conducted a systematic search for randomized controlled trials (RCTs) comparing temporary ileostomy with temporary colostomy in MEDLINE, the Cochrane database, evidence-based medicine reviews and the American College of Physicians journal club, as well as relevant reference lists in journal articles. Five RCTs were found and included in this meta-analysis. All complications were abstracted and compared between groups. All complications were also assessed using tests of statistical heterogeneity, pooling of risk ratios using Mantel-Haenszel fixed effects and DerSimonian and Laird random effects. Clinical heterogeneity was investigated by examining the methodology and selection of patients described in each trial.
Temporary colostomy was significantly more likely to cause stoma complications in colorectal cancer patients undergoing elective resections, and also more likely to cause infectious and wound complications. Temporary ileostomy tended to cause more post-closure surgical complications.
There is not yet a strong case for the superiority of one temporary diverting stoma over another for all colorectal patients. In this regard, a large, well-conducted RCT is still needed.
比较结直肠疾病患者行临时性回肠造口术和临时性结肠造口术的并发症。
两名独立研究人员在医学文献数据库(MEDLINE)、考克兰数据库、循证医学综述以及美国医师协会杂志俱乐部中系统检索比较临时性回肠造口术和临时性结肠造口术的随机对照试验(RCT),以及期刊文章中的相关参考文献列表。共找到5项RCT并纳入该荟萃分析。提取并比较两组间的所有并发症。还使用统计异质性检验评估所有并发症,采用曼特尔-亨塞尔固定效应模型和德西蒙尼安与莱尔德随机效应模型合并风险比。通过检查各试验中描述的方法和患者选择来研究临床异质性。
在接受择期手术的结直肠癌患者中,临时性结肠造口术显著更易导致造口并发症,也更易引发感染和伤口并发症。临时性回肠造口术往往会导致更多闭合后手术并发症。
对于所有结直肠疾病患者,尚无充分证据表明一种临时性转流造口术优于另一种。在这方面,仍需要一项大规模、实施良好的RCT。