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人类自然流产中三体的起源。

Origin of trisomies in human spontaneous abortions.

作者信息

Hassold T, Matsuyama A

出版信息

Hum Genet. 1979 Feb 15;46(3):285-94. doi: 10.1007/BF00273312.

Abstract

Chromosome heteromorphisms of 34 trisomic abortuses and their parents were compared to determine the origin of the extra chromosome. Fourteen of the trisomies were maternal in origin, ten resulting from a first-meiotic-division error and four from either first- or second-meiotic-division errors. No paternally derived trisomy was identified.

摘要

比较了34例三体性流产胎儿及其父母的染色体异态性,以确定额外染色体的来源。其中14例三体性源于母体,10例由第一次减数分裂错误导致,4例由第一次或第二次减数分裂错误导致。未发现父源性三体。

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