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重复桑拿治疗对慢性心力衰竭患者室性心律失常的影响。

Effects of repeated sauna treatment on ventricular arrhythmias in patients with chronic heart failure.

作者信息

Kihara Takashi, Biro Sadatoshi, Ikeda Yoshiyuki, Fukudome Tsuyoshi, Shinsato Takuro, Masuda Akinori, Miyata Masaaki, Hamasaki Shuichi, Otsuji Yutaka, Minagoe Shinichi, Akiba Suminori, Tei Chuwa

机构信息

Department of Cardiovascular, Graduate School of Medicine, Kagoshima University, Sakuragaoka, Kagoshima, Japan.

出版信息

Circ J. 2004 Dec;68(12):1146-51. doi: 10.1253/circj.68.1146.

Abstract

BACKGROUND

The aim of the present study was to determine whether repeated 60 degrees C sauna treatment improves cardiac arrhythmias in chronic heart failure (CHF) patients, because ventricular arrhythmias are an important therapeutic target in CHF.

METHODS AND RESULTS

Thirty patients (59+/-3 years) with New York Heart Association functional class II or III CHF and at least 200 premature ventricular contractions (PVCs)/24 h assessed by 24-h Holter recordings were studied. They were randomized into sauna-treated (n=20) or non-treated (n=10) groups. The sauna-treated group underwent a 2-week program of a daily 60 degrees C far infrared-ray dry sauna for 15 min, followed by 30 min bed rest with blankets, for 5 days per week. Patients in the non-treated group had bed rest in a temperature-controlled room (24 degrees C) for 45 min. The total numbers of PVCs/24 h in the sauna-treated group decreased compared with the non-treated group [848+/-415 vs 3,097+/-1,033/24 h, p<0.01]. Heart rate variability (SDNN, standard deviation of normal-to-normal beat interval) increased [142+/-10 (n=16) vs 112+/-11 ms (n=8), p<0.05] and plasma brain natriuretic peptide concentrations decreased [229+/-54 vs 419+/-110 pg/ml, p<0.05] in the sauna-treated group compared with the non-treated group.

CONCLUSION

Repeated sauna treatment improves ventricular arrhythmias in patients with CHF.

摘要

背景

本研究的目的是确定重复进行60摄氏度的桑拿治疗是否能改善慢性心力衰竭(CHF)患者的心律失常,因为室性心律失常是CHF的一个重要治疗靶点。

方法与结果

对30例纽约心脏协会心功能II级或III级的CHF患者(年龄59±3岁)进行研究,通过24小时动态心电图记录评估,这些患者每24小时至少有200次室性早搏(PVCs)。他们被随机分为桑拿治疗组(n = 20)和未治疗组(n = 10)。桑拿治疗组进行为期2周的每日60摄氏度远红外线干蒸桑拿15分钟,随后盖着毯子卧床休息30分钟,每周进行5天。未治疗组的患者在温度控制在24摄氏度的房间卧床休息45分钟。与未治疗组相比,桑拿治疗组每24小时的PVCs总数减少[848±415 vs 3097±1033/24小时,p<0.01]。与未治疗组相比,桑拿治疗组的心率变异性(SDNN,正常心跳间期的标准差)增加[142±10(n = 16)vs 112±11毫秒(n = 8),p<0.05],血浆脑钠肽浓度降低[229±54 vs 419±110 pg/ml,p<0.05]。

结论

重复桑拿治疗可改善CHF患者的室性心律失常。

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