Department of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado.
Department of Human Physiology, University of Oregon, Eugene, Oregon.
J Appl Physiol (1985). 2021 Jun 1;130(6):1684-1704. doi: 10.1152/japplphysiol.00141.2020. Epub 2021 Apr 1.
Cardiovascular diseases (CVD) are the leading cause of death worldwide, and novel therapies are drastically needed to prevent or delay the onset of CVD to reduce the societal and healthcare burdens associated with these chronic diseases. One such therapy is "heat therapy," or chronic, repeated use of hot baths or saunas. Although using heat exposure to improve health is not a new concept, it has received renewed attention in recent years as a growing number of studies have demonstrated robust and widespread beneficial effects of heat therapy on cardiovascular health. Here, we review the existing literature, with particular focus on the molecular mechanisms that underscore the cardiovascular benefits of this practice.
心血管疾病（CVD）是全球范围内的主要死因，迫切需要新的治疗方法来预防或延迟 CVD 的发生，以减轻与这些慢性疾病相关的社会和医疗负担。其中一种治疗方法是“热疗”，即长期、反复使用热水浴或桑拿。虽然利用热暴露来改善健康不是一个新概念，但近年来随着越来越多的研究表明热疗对心血管健康具有强大而广泛的有益影响，它重新引起了人们的关注。在这里，我们回顾了现有文献，特别关注了支撑这种做法对心血管有益的分子机制。
