刺激后的小鼠脾细胞中脂肪酶释放增加。
Enhanced release of lipase from stimulated mouse spleen cells.
作者信息
Okada H, Cyong J
出版信息
Immunology. 1979 Feb;36(2):307-11.
Abstract
We detected lipase activity in an homogenate of mouse spleen- and lymph node cells by using [3H]-triolein as a lipase substrate. Lipase activity was also detected in an homogenate of human peripheral blood lymphocytes. Furthermore, in mouse spleen cell culture medium we observed increased lipase activity following stimulation of mouse spleen cells with phytohaemagglutinin (PHA) as well as allogeneic spleen cells. Therefore, we suggest that lipase may be a kind of lymphokine.
摘要
我们通过使用[3H] - 三油酸甘油酯作为脂肪酶底物，在小鼠脾脏和淋巴结细胞的匀浆中检测到了脂肪酶活性。在人外周血淋巴细胞的匀浆中也检测到了脂肪酶活性。此外，在小鼠脾细胞培养基中，我们观察到在用植物血凝素（PHA）以及同种异体脾细胞刺激小鼠脾细胞后，脂肪酶活性增加。因此，我们认为脂肪酶可能是一种淋巴因子。
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本文引用的文献
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Cytotoxic factor demonstrated in lymph node extract.在淋巴结提取物中证实存在细胞毒性因子。
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Primary immune response in cultures of spleen cells.脾细胞培养中的初次免疫反应。
Lancet. 1967 Dec 16;2(7529):1279-81. doi: 10.1016/s0140-6736(67)90393-5.
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Histochemical studies on fatty acid in lymphocyte-mediated immune reaction.淋巴细胞介导免疫反应中脂肪酸的组织化学研究。
Immunology. 1976 May;30(5):763-7.
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