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后路腰椎椎间融合内固定术后并发硬膜外脓肿和椎间盘炎:一例报告

Epidural abscess and discitis complicating instrumented posterior lumbar interbody fusion: a case report.

作者信息

Carmouche Jonathan J, Molinari Robert W

机构信息

University of Rochester School of Medicine and Dentistry, Department of Orthopaedic Surgery, Spine Division, Rochester, New York, USA.

出版信息

Spine (Phila Pa 1976). 2004 Dec 1;29(23):E542-6. doi: 10.1097/01.brs.0000146802.38753.38.

Abstract

STUDY DESIGN

A case of epidural abscess and discitis following instrumented PLIF using a single carbon fiber interbody cage is presented.

OBJECTIVE

To describe a previously unreported complication of epidural abscess and discitis following posterior lumbar interbody fusion using a single carbon fiber cage.

SUMMARY OF BACKGROUND DATA

Various complications have been reported with PLIF. These include graft migration, pseudarthrosis, implant subsidence, epidural hemorrhage, incidental durotomy, arachnoiditis, transient or permanent neurologic deficits, persistence of pain, and wound infections. There are no reported cases of epidural abscess or refractory discitis associated with PLIF.

METHODS

A 35-year-old infantryman on active duty with chronic low back pain and single-level lumbar disc degeneration underwent instrumented PLIF after reporting no improvement with 3 years of extension-based physical therapy and nonsteroidal pain medications. His back pain was reported improved at 6 weeks after surgery. At 12 weeks after surgery, he presented to the emergency department with intense back pain and fevers. Laboratory data were remarkable for elevated erythrocyte sedimentation rate (118) and C-reactive protein (38). Initial imaging studies, including a lumbar MRI, did not demonstrate any abnormalities. The patient continued to spike fevers, and a repeat lumbar MRI 1 week later clearly demonstrated the presence of an epidural abscess at the level of the PLIF surgery. The patient was treated with surgical debridement and epidural abscess drainage. The interbody cage was left in place. Surgical cultures identified Staphylococcus aureus as the pathogen, and the patient was placed on intravenous vancomycin. During the ensuing 3 weeks, his clinical symptoms worsened and his radiographs demonstrated lucency in the region of his interbody cage. Repeat debridement was performed, and his interbody cage and pedicle screw instrumentation were removed 4 months after initial surgery.

RESULTS

The disc space infection resolved following removal of the implants. Radiographs at 6 months after instrumentation removal demonstrated solid bilateral posterolateral arthrodesis. The patient returned to active duty 1 year after his initial surgery, reporting that his back pain was reduced compared with his preoperative level.

CONCLUSIONS

There is a paucity of literature on epidural abscess and discitis as complications associated with PLIF. In this case, the infection persisted despite surgical debridement and intravenous antibiotics. The patient ultimately required removal of the interbody implant and posterior instrumentation. The patient developed solid posterolateral arthrodesis despite the presence of deep infection, which led to early implant removal 4 months after the initial surgery. This case underscores the potential importance of concomitant posterolateral fusion, particularly following wide laminectomy and facetectomy required for PLIF.

摘要

研究设计

本文报告1例使用单根碳纤维椎间融合器进行后路腰椎椎间融合术(PLIF)后发生硬膜外脓肿和椎间盘炎的病例。

目的

描述一种此前未报道过的使用单根碳纤维椎间融合器进行后路腰椎椎间融合术后发生硬膜外脓肿和椎间盘炎的并发症。

背景资料总结

已有多种PLIF相关并发症的报道。这些并发症包括移植物移位、假关节形成、植入物下沉、硬膜外出血、意外硬膜切开、蛛网膜炎、短暂或永久性神经功能缺损、疼痛持续存在以及伤口感染。尚无与PLIF相关的硬膜外脓肿或难治性椎间盘炎的病例报道。

方法

一名35岁现役步兵,患有慢性下腰痛和单节段腰椎间盘退变,在接受了3年基于伸展的物理治疗和非甾体类止痛药治疗后未见改善,遂接受了器械辅助的PLIF手术。据报告,他术后6周背痛有所改善。术后12周,他因剧烈背痛和发热前往急诊科就诊。实验室检查数据显示红细胞沉降率(118)和C反应蛋白(38)升高。包括腰椎MRI在内的初始影像学检查未显示任何异常。患者持续发热,1周后复查腰椎MRI清楚地显示在PLIF手术节段存在硬膜外脓肿。患者接受了手术清创和硬膜外脓肿引流。椎间融合器保留原位。手术培养确定病原体为金黄色葡萄球菌,患者接受静脉注射万古霉素治疗。在随后的3周内,他的临床症状恶化,X线片显示椎间融合器区域出现透亮区。再次进行了清创,并在初次手术后4个月取出了椎间融合器和椎弓根螺钉内固定装置。

结果

取出植入物后椎间盘间隙感染得到解决。取出内固定装置6个月后的X线片显示双侧后外侧坚固融合。患者在初次手术后1年重返现役,报告称与术前相比背痛减轻。

结论

关于硬膜外脓肿和椎间盘炎作为PLIF相关并发症的文献较少。在本病例中,尽管进行了手术清创和静脉使用抗生素,感染仍持续存在。患者最终需要取出椎间植入物和后路内固定装置。尽管存在深部感染,但患者仍形成了坚固的后外侧融合,这导致在初次手术后4个月提前取出植入物。本病例强调了同期后外侧融合的潜在重要性,尤其是在PLIF所需的广泛椎板切除术和关节突切除术后。

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