Kaushik N, Saba Z, Rosenfeld H, Patel H T, Martin K, Reinhartz O, Lamberti J J
General Pediatrics, Children's Hospital and Research Center Oakland, 747 52nd Street, Oakland, CA 94609, USA.
Pediatr Cardiol. 2005 Sep-Oct;26(5):707-9. doi: 10.1007/s00246-004-0896-x.
An isolated left common carotid artery (LCA) is an extremely rare condition with only four reported cases. In each case, the isolated carotid artery connects to the right or left pulmonary artery via the ductus arteriosus and the embryologic basis for the abnormalities is believed to reflect an error in the development of the branchial arches. We present a case of an isolated LCA connecting to the main pulmonary artery in association with a right aortic arch and an anomalous origin of the left subclavian artery from the descending aorta. The left ligamentus arteriosus was identified separately. This may represent a disturbance in the septation of the truncoaortic sac secondary to abnormal migration of neural crest cells rather than a pure developmental anomaly of the branchial arches.
孤立性左颈总动脉(LCA)是一种极为罕见的病症,仅有4例报道。在每例病例中,孤立的颈动脉通过动脉导管与右或左肺动脉相连,并且据信这些异常的胚胎学基础反映了鳃弓发育过程中的错误。我们报告一例孤立性左颈总动脉与主肺动脉相连,同时合并右主动脉弓及左锁骨下动脉起自降主动脉异常的病例。单独发现了左动脉韧带。这可能代表了继发于神经嵴细胞异常迁移的主动脉干囊分隔紊乱,而非鳃弓的单纯发育异常。