Tychinsky V, Kretushev A, Vyshenskaja T
Moscow State Institute for Radioengineering, Electronics and Automation, Vernadsky Pr. 78, 117454, Moscow, Russia.
Eur Biophys J. 2004 Dec;33(8):700-5. doi: 10.1007/s00249-004-0414-3. Epub 2004 May 20.
The membrane potential of mitochondria determines, to a large extent, their functional state and the response to the changing conditions of the environment. A correlation was found between the changes in the optical characteristics of isolated mitochondria and the composition of the incubation medium, which determines the potential of the inner mitochondrial membrane. The measurements performed by the method of coherent phase microscopy made it possible to establish a linear dependence of the phase height on the value of the membrane potential and to calculate the electrooptical constant, K approximately equal to (3-4) x 10(-7) m/V.
