Oros Ana-Maria, Shah N Jon
Institute of Medicine, Research Centre Jiilich, 52425 Jülich, Germany.
Phys Med Biol. 2004 Oct 21;49(20):R105-53. doi: 10.1088/0031-9155/49/20/r01.
Hyperpolarized gases have found a steadily increasing range of applications in nuclear magnetic resonance (NMR) and NMR imaging (MRI). They can be regarded as a new class of MR contrast agent or as a way of greatly enhancing the temporal resolution of the measurement of processes relevant to areas as diverse as materials science and biomedicine. We concentrate on the properties and applications of hyperpolarized xenon. This review discusses the physics of producing hyperpolarization, the NMR-relevant properties of 129Xe, specific MRI methods for hyperpolarized gases, applications of xenon to biology and medicine, polarization transfer to other nuclear species and low-field imaging.
超极化气体在核磁共振（NMR）和核磁共振成像（MRI）中的应用范围一直在稳步扩大。它们可被视为一类新型的磁共振造影剂，或者是一种极大提高与材料科学和生物医学等不同领域相关过程测量时间分辨率的方法。我们专注于超极化氙的性质和应用。本综述讨论了产生超极化的物理过程、129Xe的与NMR相关的性质、超极化气体的特定MRI方法、氙在生物学和医学中的应用、向其他核素的极化转移以及低场成像。
