Reid Thomas M, Wolf Caitlin A, Kraemer Christopher M, Lee Susannie C, Baird Michael L, Lee Richard F
DNA Diagnostics Center, Fairfield, OH 45014, USA.
J Forensic Sci. 2004 Nov;49(6):1262-4.
Fifty known siblings and fifty unrelated pairs were genotyped using the ABI Identifiler STR system and sibship indices computed for each pair. Combined sibship indices (CSIs) for the known siblings ranged from less than 10 to greater than 1 billion. CSIs for the unrelated pairs ranged from 4.5 x 10(-8) to 0.12. In the known sibling group the percentage of loci where both alleles matched was approximately 40%, while the percentage of loci where neither matched was approximately 10%. In the non-sibling group, the percentage of loci where both alleles matched was approximately 6%, while the percentage of loci where neither matched was approximately 45%. Interestingly, the percentage of loci where a single allele matched was the same in both the known siblings and unrelated pairs, approximately 50%.
使用ABI Identifiler STR系统对50对已知的兄弟姐妹和50对无关个体进行基因分型，并为每对个体计算同胞关系指数。已知兄弟姐妹的综合同胞关系指数（CSI）范围从小于10到大于10亿。无关个体对的CSI范围从4.5×10⁻⁸到0.12。在已知的兄弟姐妹组中，两个等位基因都匹配的位点百分比约为40%，而两个等位基因都不匹配的位点百分比约为10%。在非兄弟姐妹组中，两个等位基因都匹配的位点百分比约为6%，而两个等位基因都不匹配的位点百分比约为45%。有趣的是，在已知的兄弟姐妹和无关个体对中，单个等位基因匹配的位点百分比相同，约为50%。
