Schmidtová Katarína, Sirot'áková Mária, Kocisová Monika, Mechírová Eva
University P. J. Safárik, Faculty of Medicine, Kosice, Slovak Republic: Department of Anatomy.
Acta Medica (Hradec Kralove). 2004;47(3):205-8.
The presence and intraorgan distribution of the acetylcholinesterase (AChE)-positive nerve structures in the guinea-pig spleen were studied by means of the direct thiocholine method. Visualized AChE-positive nerve fibres entered the guinea-pig spleen at its hilum in the vicinity of the splenic artery branches and intra parenchyma were gradually distributed to form thicker periarterial nerves and also fine adventitial nerve plexus. In described topography the AChE-positive nerve fibres were identified in association with the central artery running through the white pulp. Some of the perivascular nerve fibres associated with the central artery extended away and passed into the periarterial lymphatic sheath (PALS) to reach the marginal zone and in continuation entered into the mantle zone of lymphatic follicles. Several AChE-positive nerve fibres were seen in the red pulp but less in the splenic capsule. We did not find any AChE-positive nerve cells in the guinea-pig spleen.
采用直接硫代胆碱法研究了豚鼠脾脏中乙酰胆碱酯酶（AChE）阳性神经结构的存在及其在器官内的分布。可见AChE阳性神经纤维在脾门处脾动脉分支附近进入豚鼠脾脏，在实质内逐渐分布，形成较粗的动脉周围神经以及细小的外膜神经丛。在所描述的解剖位置中，AChE阳性神经纤维与贯穿白髓的中央动脉相关。一些与中央动脉相关的血管周围神经纤维向外延伸，进入动脉周围淋巴鞘（PALS），到达边缘区，并继续进入淋巴滤泡的套区。在红髓中可见数条AChE阳性神经纤维，但在脾被膜中较少。在豚鼠脾脏中未发现任何AChE阳性神经细胞。
