羊踯躅花中的二萜类化合物。

Diterpenoids from the flowers of Rhododendron molle.

作者信息

Chen Shao-Nong, Zhang Hua-Ping, Wang Li-Quan, Bao Guan-Hu, Qin Guo-Wei

机构信息

Shanghai Institute of Materia Medica, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, People's Republic of China.

出版信息

J Nat Prod. 2004 Nov;67(11):1903-6. doi: 10.1021/np040012o.

DOI:10.1021/np040012o

PMID:15568787

Abstract

Five new grayanane-type diterpenoids, rhodomolleins IX (1), X (2), XI (3), XII (4), and XIII (5), a new kalmane-type diterpenoid, rhodomollein XIV (6), and seven known diterpenoids, grayanotoxin II, rhodomolleins I and XIX, rhodojaponins II, III, and VI (7), and kalmanol, were isolated from the flowers of Rhododendron molle. The structures of 1-6 were elucidated by spectroscopic methods, including 1D and 2D NMR experiments.

摘要

从羊踯躅花中分离得到5个新的木藜芦烷型二萜，闹羊花素IX（1）、X（2）、XI（3）、XII（4）和XIII（5），1个新的贝壳杉烷型二萜，闹羊花素XIV（6），以及7个已知二萜，即灰毒素II、闹羊花素I和XIX、杜鹃毒素II、III和VI（7）以及贝壳杉醇。通过包括一维和二维核磁共振实验在内的光谱方法阐明了化合物1 - 6的结构。