Salamah A A
Botany and Microbiology Department, College of Science, King Saud University, Riyadh, Saudi Arabia.
Microbiologica. 1992 Jan;15(1):75-8.
The effect of pigmentation and coagulase on the virulence of a capsule-lacking Staphylococcus aureus were studied using iron-compromised mice. The presence of either coagulase or pigmentation maintained the viability of this bacterium in the peritoneal cavity. Both coagulase and pigmentation, however, lead not only to maintained viability, but also to its proliferation in the peritoneal macrophages. The iron was found to enhance the virulence of this bacterium, but iron enhancement was contingent on the presence of either pigmentation or coagulase or preferably both.
利用缺铁小鼠研究了色素沉着和凝固酶对无荚膜金黄色葡萄球菌毒力的影响。凝固酶或色素沉着的存在维持了这种细菌在腹腔内的生存能力。然而，凝固酶和色素沉着不仅导致其生存能力的维持，还导致其在腹腔巨噬细胞中的增殖。发现铁可增强这种细菌的毒力，但铁的增强取决于色素沉着或凝固酶的存在，或最好两者都存在。
