Sheahan P, Fitzgibbon J, O'Leary G, Lee G
Department of Otolaryngology, Head and Neck Surgery, South Infirmary, Victoria Hospital, Cork, Ireland.
Surgeon. 2004 Jun;2(3):152-6. doi: 10.1016/s1479-666x(04)80076-3.
Fine needle aspiration biopsy (FNAB) is now well established in the assessment of cervical masses. The purpose of the present study is to review the efficacy of this procedure, as well as to identify any pitfalls that may limit its usefulness.
One hundred and ninety aspirations of neck masses performed over a recent five-year period were reviewed. The definitive diagnosis of the mass was determined in each case by review of the patients' case notes.
Thirty seven per cent of all neck lumps were malignant. The most common cause for a false-negative result, in the case of a carcinomatous mass when an adequate sample had been obtained, was a cystic neoplasm. One quarter of all cystic lateral cervical masses not considered suspicious for malignancy by FNAB turned out to be malignant.
Repeating FNAB in cases where the original result is negative for carcinoma may increase the sensitivity of FNAB in the detection of cystic carcinomas.
细针穿刺活检（FNAB）目前在颈部肿块评估中已得到广泛应用。本研究的目的是回顾该操作的有效性，并确定可能限制其效用的任何陷阱。
回顾了最近五年内对颈部肿块进行的190次穿刺。通过查阅患者病历确定每个病例中肿块的最终诊断。
所有颈部肿块中有37%为恶性。在获取了足够样本的癌性肿块病例中，假阴性结果最常见的原因是囊性肿瘤。FNAB未将其视为恶性可疑的所有囊性颈侧肿块中，有四分之一最终被证明是恶性的。
在最初结果为癌阴性的病例中重复进行FNAB可能会提高FNAB检测囊性癌的敏感性。
