Fulciniti F, Califano L, Zupi A, Vetrani A
Faculty of Medicine and Surgery Federico II University of Naples, Italy.
J Oral Maxillofac Surg. 1997 Oct;55(10):1094-7. doi: 10.1016/s0278-2391(97)90288-3.
Fine-needle aspiration biopsy (FNAB) is frequently used in the diagnosis of lesions occurring in the head and neck region. This study evaluated the correlation between the findings on FNAB and the histological findings observed after surgery.
A review of 218 patients who underwent FNAB of a head or neck tumor was performed. Cytological reports were classified into the following diagnostic categories: negative or positive for malignant cells and unsatisfactory. False-positive, false-negative, true-positive (sensitivity), and true-negative (specificity) rates were calculated.
Twelve specimens did not allow an adequate diagnosis (5.5%). Among benign tumors, 96.2% of the cases were correctly diagnosed, and 3.8% were nondiagnostic specimens. Among malignant tumors, 86.4% of cases were correctly identified. There were two (3.4%) false-negatives and six (10.2%) nondiagnostic specimens, with a total false-negative rate of 13.6%.
Sampling errors present a minor problem with FNAB. Most nondiagnostic or incorrect specimens were caused by nonhomogenous lesions, with poor placement of the needle and an insufficient amount of aspirated material. FNAB is a useful modality for the diagnosis of head and neck masses.
细针穿刺活检（FNAB）常用于诊断头颈部区域出现的病变。本研究评估了FNAB的检查结果与手术后观察到的组织学检查结果之间的相关性。
对218例行头颈部肿瘤FNAB的患者进行回顾性研究。细胞学报告分为以下诊断类别：恶性细胞阴性或阳性以及不满意。计算假阳性、假阴性、真阳性（敏感性）和真阴性（特异性）率。
12份标本无法做出充分诊断（5.5%）。在良性肿瘤中，96.2%的病例被正确诊断，3.8%为无法诊断的标本。在恶性肿瘤中，86.4%的病例被正确识别。有2例（3.4%）假阴性和6例（10.2%）无法诊断的标本，总假阴性率为13.6%。
抽样误差在FNAB中是一个小问题。大多数无法诊断或错误的标本是由病变不均匀、针放置不当以及吸出材料量不足引起的。FNAB是诊断头颈部肿块的一种有用方法。
