Pomara Giorgio, Pastina Ilaria, Simone Maurizio, Casale Paolo, Marchetti Gabriella, Francesca Francesco
Department of Surgery, Urology Unit, S, Chiara Hospital, Pisa, Italy.
BMC Cancer. 2004 Dec 3;4:90. doi: 10.1186/1471-2407-4-90.
Almost one-third of all penile metastases are detected at the same time as a primary tumor, whereas the remaining two-thirds are detected a mean of 18 months after the discovery of the primary tumor. Cutaneous metastasis of transitional cell carcinoma (TCC) is extremely rare and generally accepted as the late manifestation of a systemic spread.
We report the first case of simultaneous penile and lung metastases from a primary TCC of the renal pelvis in a 76-year-old man, that occurred 8 years after a left nephroureterectomy.
This case report underscores the importance of physical examinations of the skin of patients who undergo surgical procedures for TCC from bladder as well as from the upper urinary tract, including those seemingly without metastatic disease, because of the possibility of skin and penile metastatic spread.
几乎三分之一的阴茎转移瘤是在发现原发性肿瘤的同时被检测到的，而其余三分之二则是在原发性肿瘤被发现后平均18个月被检测到。移行细胞癌（TCC）的皮肤转移极为罕见，通常被认为是全身扩散的晚期表现。
我们报告了首例76岁男性肾盂原发性TCC同时发生阴茎和肺部转移的病例，该病例发生在左肾输尿管切除术后8年。
本病例报告强调了对因膀胱以及上尿路TCC而接受手术的患者进行皮肤体格检查的重要性，包括那些看似没有转移性疾病的患者，因为存在皮肤和阴茎转移扩散的可能性。
