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来自绞股蓝的新型达玛烷型糖苷。

Novel dammarane-type glycosides from Gynostemma pentaphyllum.

作者信息

Yin Feng, Hu Lihong, Pan Ruixiang

机构信息

National Center for Drug Screening, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 189 Guo-Shou-Jing Road, Shanghai 201203, China.

出版信息

Chem Pharm Bull (Tokyo). 2004 Dec;52(12):1440-4. doi: 10.1248/cpb.52.1440.

DOI:10.1248/cpb.52.1440
PMID:15577241
Abstract

Three new dammarane glycosides (1-3), together with five known compounds, gypenoside LXIX (4), gylongiposide I (5), gypenoside XLVIII (6), allantion (7) and vitexin (8) were isolated from the MeOH extract of the aerial parts of Gynostemma pentaphyllum. Compounds 5, 7, and 8 were isolated from this plant for the first time. Their structures were elucidated by 1D and 2D NMR spectra interpretation as well as by chemical degradation.

摘要

从绞股蓝地上部分的甲醇提取物中分离得到3个新的达玛烷型糖苷(1-3),以及5个已知化合物,绞股蓝皂苷LXIX(4)、绞股蓝皂苷I(5)、绞股蓝皂苷XLVIII(6)、尿囊素(7)和牡荆素(8)。化合物5、7和8首次从该植物中分离得到。通过一维和二维核磁共振波谱解析以及化学降解对它们的结构进行了阐明。

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