益智中的达玛烷型糖苷和长链倍半萜糖苷。
Dammarane-type glycosides and long chain sesquiterpene glycosides from Gynostemma yixingense.
机构信息
School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, PR China.
出版信息
Fitoterapia. 2010 Jun;81(4):248-52. doi: 10.1016/j.fitote.2009.09.009. Epub 2009 Sep 23.
A new dammarane-type glycoside and a new long chain sesquiterpene glycoside, along with nine known compounds 20(S)-ginsenoside Rh1 (3), 20(R)-ginsenoside Rh1 (4), ginsenoside F1 (4), amarantholidoside IV (6), ginsenoside Rc (7), 20(S)-ginsenoside Rg2 (8), 20(R)-ginsenoside Rg2 (9), ginsenoside Rd (10) and gypenoside XLVI (11) were isolated from Gynostemma yixingense. The structures of the new compounds were determined on the basis of spectroscopic analysis, including 1D-, 2D-NMR and ESI-MS techniques as well as by comparison of the spectral data with those of related compounds as 2 alpha,3beta,20(S)-trihydroxydammar-24-ene-3-O-[beta-D-glucopyranosyl((1-->2)-beta-D-glucopyranosyl]-20-O-[beta-D-xylopyranosyl((1-->6)-beta-D-glucopyranoside] (1) (2E,6E)-10-beta-D-glucopyranosyl-1,10,11-trihydroxy-3,7,11-trimethyldodeca-2,6-diene (2).
从益智中分离得到了一个新的达玛烷型糖苷和一个新的长链倍半萜糖苷，以及 9 个已知化合物 20(S)-人参皂苷 Rh1(3)、20(R)-人参皂苷 Rh1(4)、人参皂苷 F1(4)、苋醇苷 IV(6)、人参皂苷 Rc(7)、20(S)-人参皂苷 Rg2(8)、20(R)-人参皂苷 Rg2(9)、人参皂苷 Rd(10)和绞股蓝皂苷 XLVI(11)。新化合物的结构是根据光谱分析确定的，包括 1D-、2D-NMR 和 ESI-MS 技术以及与相关化合物的光谱数据进行比较，如 2α,3β,20(S)-三羟基达玛-24-烯-3-O-[β-D-吡喃葡萄糖基((1-->2)-β-D-吡喃葡萄糖基]-20-O-[β-D-吡喃木糖基((1-->6)-β-D-吡喃葡萄糖苷] (1) (2E,6E)-10-β-D-吡喃葡萄糖基-1,10,11-三羟基-3,7,11-三甲基十二烷-2,6-二烯 (2)。
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