来自台湾柳珊瑚脆弱柳珊瑚的刺柏烷二萜类化合物。

Briarane diterpenoids from the formosan gorgonian Coral Junceella fragilis.

作者信息

Sung Ping-Jyun, Lin Mei-Ru, Fang Lee-Shing

机构信息

National Museum of Marine Biology and Aquarium, Checheng, Pingtung, Taiwan, ROC.

出版信息

Chem Pharm Bull (Tokyo). 2004 Dec;52(12):1504-6. doi: 10.1248/cpb.52.1504.

DOI:10.1248/cpb.52.1504

PMID:15577258

Abstract

A new trihydroxy briarane-related diterpenoid, junceellolide I (1), along with a known metabolite, (1R,2R,5Z,7R,8S,9R,10R,12R,14R,17S)-2,14-diacetoxy-8,17-epoxy-9,12-dihydroxybriara-5,11(20)-dien-19-one (2), have been isolated from the gorgonian coral Junceella fragilis, collected off the southern Taiwan coast. The structure, including the relative configuration of the new compound 1, was elucidated by the combination of spectral data, particularly in high-resolution 1H- and 13C-NMR spectroscopy utilizing COSY, HMBC, HMQC, and NOESY experiments.

摘要

从台湾南部海岸采集的脆弱软柳珊瑚（Junceella fragilis）中分离出一种新的与三羟基蔷薇烷相关的二萜类化合物——柔扁枝杉内酯I（1），以及一种已知的代谢产物（1R,2R,5Z,7R,8S,9R,10R,12R,14R,17S）-2,14-二乙酰氧基-8,17-环氧-9,12-二羟基蔷薇-5,11(20)-二烯-19-酮（2）。通过光谱数据，特别是利用COSY、HMBC、HMQC和NOESY实验的高分辨率1H-和13C-NMR光谱，阐明了新化合物1的结构，包括其相对构型。