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苯二氮䓬类药物依赖

Benzodiazepine dependence.

作者信息

Khong Eric, Sim Moira G, Hulse Gary

机构信息

Drug and Alcohol Office, Centre for Postgraduate Medicine, Edith Cowan University.

出版信息

Aust Fam Physician. 2004 Nov;33(11):923-6.

Abstract

BACKGROUND

Benzodiazepine dependency can occur as a result of treatment for anxiety disorders or sleep disturbance. While benzodiazepine withdrawal can be challenging, cessation of use can be even more difficult if there are other comorbidities such as oestrogen deficiency with vasomotor symptoms and anxiety disorders.

OBJECTIVE

This article provides practical information for general practitioners in the management of patients with benzodiazepine dependence.

DISCUSSION

Some patients may have common medical presentations and coexisting drug dependence. It is often difficult to separate these two issues. In the case of benzodiazepine dependence, gradual withdrawal over time and nonpharmacological treatment of the symptoms of withdrawal such as anxiety or insomnia is effective. Better outcomes are achieved where the GP discusses and plans strategies well in advance with the patient. Treatment often involves multiple interventions from various health professionals. General practitioners are ideally placed to coordinate such treatment.

摘要

背景

苯二氮䓬类药物依赖可能是焦虑症或睡眠障碍治疗的结果。虽然苯二氮䓬类药物戒断具有挑战性,但如果存在其他合并症,如伴有血管舒缩症状的雌激素缺乏和焦虑症,停用药物可能会更加困难。

目的

本文为全科医生管理苯二氮䓬类药物依赖患者提供实用信息。

讨论

一些患者可能有常见的医学表现和并存的药物依赖。通常很难区分这两个问题。对于苯二氮䓬类药物依赖,随着时间的推移逐渐停药以及对戒断症状(如焦虑或失眠)进行非药物治疗是有效的。如果全科医生提前与患者充分讨论并制定策略,会取得更好的效果。治疗通常涉及来自不同健康专业人员的多种干预措施。全科医生最适合协调这种治疗。

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