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[城市基层医疗保健中心老年女性苯二氮䓬类药物使用增加]

[Increased benzodiazepine use in elderly women attending urban primary health care centers].

作者信息

Bejarano Romero Ferran, Piñol Moreso Josep Lluís, Mora Gilabert Núria, Claver Luque Pere, Brull López Núria, Basora Gallisa Josep

机构信息

Farmacología Clínica. Direcció d'Atenció Primària Tarragona-Reus. Institut Català de la Salut. Tarragona. España.

出版信息

Aten Primaria. 2008 Dec;40(12):617-21. doi: 10.1016/s0212-6567(08)75695-6.

Abstract

OBJECTIVE

To determine the overall prevalence of the chronic use of benzodiazepines and similar drugs in primary care.

DESIGN

Observational, cross-sectional study.

SETTING

Healthcare centres of the Reus-Altebrat Primary Care Service, Tarragona, Spain.

PARTICIPANTS

Patients older than 15 years, on prolonged treatment with benzodiazepines or similar drugs.

MEASUREMENTS

The variables studied were age, sex, type of healthcare centre (rural or urban), benzodiazepine, or similar drug administered and duration of treatment. RESULTS. There were 6885 patients who were on prolonged benzodiazepine or similar drug treatment, of which 70.9% were female, 73.4% were 65 years or older, and 73% attended an urban centre. The overall prevalence was 6.9%, and was higher among women than men (9.7% and 4%, respectively), and increased with age up to 27.3% among patients of 75 years or more. The stratified results showed that chronic consumption was higher among women 75 years of age or older attached to urban healthcare centres, with a prevalence of 35.7%.

CONCLUSIONS

A high percentage of our population, which includes the most fragile patients, use benzodiazepines or a similar drug in a way that is not consistent with the recommendations of clinical practice guidelines.

摘要

目的

确定基层医疗中苯二氮䓬类药物及类似药物长期使用的总体患病率。

设计

观察性横断面研究。

地点

西班牙塔拉戈纳雷乌斯 - 阿尔特布拉特基层医疗服务中心的医疗保健中心。

参与者

年龄超过15岁、正在接受苯二氮䓬类药物或类似药物长期治疗的患者。

测量指标

所研究的变量包括年龄、性别、医疗保健中心类型(农村或城市)、所使用的苯二氮䓬类药物或类似药物以及治疗持续时间。结果。共有6885名患者正在接受苯二氮䓬类药物或类似药物的长期治疗,其中70.9%为女性,73.4%年龄在65岁及以上,73%就诊于城市中心。总体患病率为6.9%,女性患病率高于男性(分别为9.7%和4%),且随年龄增长患病率上升,75岁及以上患者中患病率高达27.3%。分层结果显示,75岁及以上城市医疗保健中心的女性慢性用药率更高,患病率为35.7%。

结论

我们的人群中很大一部分,包括最脆弱的患者,使用苯二氮䓬类药物或类似药物的方式不符合临床实践指南的建议。

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