青蛙缝匠肌甘油处理纤维中肌膜延迟整流的特性

Properties of sarcolemmal delayed rectification in glycerol-treated fibers of frog sartorius muscle.

作者信息

Takeda K

出版信息

Jpn J Physiol. 1975;25(4):507-13. doi: 10.2170/jjphysiol.25.507.

DOI:10.2170/jjphysiol.25.507

Abstract

Total current-voltage relations were analyzed on nine glycerol-treated surface fibers of frog sartorius muscles in tetrodotoxin-containing isotonic normal Ringer solution. The results indicate that delayed rectification occurs in the sarcolemma on large depolarization and that delayed rectification is only partially inactivated during 1 sec of depolarization and not converted into anomalous rectification. The time to peak, the time course of inactivation and the potassium activation potential determined in glycerol-treated fibers were comparable to those analyzed previously in intact fibers. The value of the conductance increase during delayed rectification in glycerol-treated fibers appeared to be smaller than that in intact fibers.

摘要

在含有河豚毒素的等渗正常林格液中，对九条经甘油处理的青蛙缝匠肌表面纤维进行了总电流-电压关系分析。结果表明，在大的去极化时，肌膜中会出现延迟整流，并且在1秒的去极化过程中延迟整流仅部分失活，且不会转变为反常整流。在经甘油处理的纤维中测定的峰值时间、失活时间进程和钾激活电位与之前在完整纤维中分析的结果相当。经甘油处理的纤维在延迟整流期间电导增加的值似乎比完整纤维中的小。