情绪应激状态下豚鼠因噪声暴露导致的暂时性阈移

Temporary threshold shift due to noise exposure in guinea pigs under emotional stress.

作者信息

Muchnik C, Sahartov E, Peleg E, Hildesheimer M

机构信息

Department of Communication Disorders, Speech, Language and Hearing, Tel Hashomer, Israel.

出版信息

Hear Res. 1992 Feb;58(1):101-6. doi: 10.1016/0378-5955(92)90013-d.

DOI:10.1016/0378-5955(92)90013-d

PMID:1559900

Abstract

One of the factors which can affect the amount of temporary threshold shift (TTS) due to acoustic overstimulation is known to be the general metabolic state of the exposed subject. The present study was conducted to elucidate how preexisting intense emotional stress in awake guinea pigs could influence the TTS induced by exposure of 4 kHz at 120 dB SPL for 20 min. Considering the hypersympathetic activity in both 'stress' and 'noise' it was assumed that the two factors would act synergetically on the cochlear function. However, an unexpected result was obtained. The mean threshold for the stressed animals following noise exposure was significantly lower (better) than that of the controlled, sedated, guinea pigs.

摘要

已知影响因听觉过度刺激导致的暂时性阈移（TTS）量的因素之一是受暴露个体的一般代谢状态。本研究旨在阐明清醒豚鼠中预先存在的强烈情绪应激如何影响在120 dB SPL下暴露于4 kHz 20分钟所诱发的TTS。考虑到“应激”和“噪声”中均存在的交感神经活动亢进，推测这两个因素会对耳蜗功能产生协同作用。然而，却得到了一个意外的结果。噪声暴露后，应激动物的平均听阈显著低于（好于）对照的、已镇静的豚鼠。