奶用绵羊产奶量数量性状位点定位及乳蛋白基因多态性研究
Mapping quantitative trait loci for milk production and genetic polymorphisms of milk proteins in dairy sheep.
作者信息
Barillet Francis, Arranz Juan-José, Carta Antonello
机构信息
Station d'amélioration des animaux, Institut national de la recherche agronomique, BP 27, 31326 Castanet-Tolosan Cedex, France.
出版信息
Genet Sel Evol. 2005;37 Suppl 1(Suppl 1):S109-23. doi: 10.1186/1297-9686-37-S1-S109.
In this paper, we present recent advances in the molecular dissection of complex traits in dairy sheep and discuss their possible impact on breeding schemes. In the first step, we review the literature data on genetic polymorphisms and the effects of sheep alphas1-casein and beta-lactoglobulin loci. It is concluded that the results are rather inconsistent and cannot be used in dairy sheep selection. In a second step, we describe the strategy implemented in France, Italy and Spain taking advantage of the genetic maps for QTL detection. These studies were part of a European project, called "genesheepsafety", which investigated both milk production and functional traits. Preliminary QTL results are presented for production traits.
在本文中，我们介绍了奶用绵羊复杂性状分子解析方面的最新进展，并讨论了它们对育种计划可能产生的影响。第一步，我们回顾了关于遗传多态性以及绵羊αs1-酪蛋白和β-乳球蛋白基因座效应的文献数据。得出的结论是，结果相当不一致，无法用于奶用绵羊的选育。第二步，我们描述了法国、意大利和西班牙利用遗传图谱进行QTL检测所实施的策略。这些研究是一个名为“genesheepsafety”的欧洲项目的一部分，该项目对产奶量和功能性状都进行了研究。文中给出了生产性状的初步QTL结果。
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