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埃及巴尔基羊生长和产奶性能性状候选基因分析

Analysis of Candidate Genes for Growth and Milk Performance Traits in the Egyptian Barki Sheep.

作者信息

Abousoliman Ibrahim, Reyer Henry, Oster Michael, Muráni Eduard, Mourad Mosaad, Rashed Mohamed Abdel-Salam, Mohamed Ismail, Wimmers Klaus

机构信息

Institute of Genome Biology, Leibniz Institute for Farm Animal Biology, Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany.

Department of Animal and Poultry Breeding, Desert Research Center, 1 Mathaf El-Matareya st, 11753 El-Matareya, Cairo, Egypt.

出版信息

Animals (Basel). 2020 Jan 23;10(2):197. doi: 10.3390/ani10020197.

DOI:10.3390/ani10020197
PMID:31979402
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7070871/
Abstract

The most common sheep breeds of Egypt are Ossimi, Rahmani, and Barki breeds. The latter one is well adapted to the challenging desert environment, characterized by food shortage and a high temperature fluctuation. Growth performance of Barki sheep has an important economic value in terms of minimizing the shortage of mutton meat in Egypt. Further, milk production is of great importance for feeding newborn lambs. Eight candidate genes, recently associated with production traits in different breeds, were used to study the effect of genotype on lamb growth and ewe milk traits. The examined genes were and , of which one representative single nucleotide polymorphism (SNP) located in the coding region was selected for genotyping. Data from 251 Barki sheep were used in this study. Association analysis between SNPs and lamb growth traits identified rs420693815 of the gene to be significantly associated with weaning weight and average daily gain. In ewes, significant effects on milk yield and composition have been estimated for (rs420693815), (rs161082816), (rs422713690), and (rs414991449). The results indicated that these genes might be considered as interesting candidates for further investigations to improve growth and milk performance in Barki sheep.

摘要

埃及最常见的绵羊品种是奥西米、拉赫曼尼和巴尔基品种。后者非常适应具有挑战性的沙漠环境,其特点是食物短缺和温度波动大。巴尔基羊的生长性能对于减少埃及羊肉短缺具有重要的经济价值。此外,产奶量对于喂养新生羔羊非常重要。最近与不同品种生产性状相关的八个候选基因被用于研究基因型对羔羊生长和母羊产奶性状的影响。所检测的基因是[具体基因名称缺失]和[具体基因名称缺失],其中位于编码区的一个代表性单核苷酸多态性(SNP)被选择用于基因分型。本研究使用了来自251只巴尔基羊的数据。SNP与羔羊生长性状之间的关联分析确定,[具体基因名称缺失]基因的rs420693815与断奶体重和平均日增重显著相关。在母羊中,已估计[具体基因名称缺失](rs420693815)、[具体基因名称缺失](rs161082816)、[具体基因名称缺失](rs422713690)和[具体基因名称缺失](rs414991449)对产奶量和成分有显著影响。结果表明,这些基因可能被视为进一步研究以改善巴尔基羊生长和产奶性能的有趣候选基因。

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