布鲁氏菌病患者的血清铜和锌浓度

Serum copper and zinc concentrations in patients with brucellosis.

作者信息

Cesur Salih, Kocaturk Pelin Aribal, Kavas Guzin Ozelci, Aksaray Sebahat, Tezeren Deniz, Ciftci Ugur

机构信息

Tuberculosis Referance and Research Laboratory, Refik Saydam Hygiene Center, AB Blok Kat: 3 06100, Ankara, Turkey.

出版信息

J Infect. 2005 Jan;50(1):31-3. doi: 10.1016/j.jinf.2004.05.001.

DOI:10.1016/j.jinf.2004.05.001

PMID:15603837

Abstract

The aim of this study was to measure the alterations in serum trace element concentrations, including zinc (Zn) and copper (Cu) in patients with brucellosis and to compare them with the results of healthy individuals. Seventy-five subjects, 60 patients with brucellosis and 15 healthy individuals were included in this study. The serum Zn and Cu concentrations were measured by using atomic absorbtion spectrophotometer in sera of patients with brucellosis and statistically compared with those of healthy individuals. Serum Cu concentration was found to be significantly higher in patients with brucellosis than that of healthy individual (130.5+/-24.7, 96+/-8.65 microg/dl, respectively) (p < 0.01). Serum Zn concentration was lower in patients with brucellosis than those of healthy subjects (79.5 +/-13.5 and 83+/-5.59 microg/dl, respectively) (p < 0.01). Serum trace element concentrations showed significant alterations in patients with brucellosis compared with healthy subjects.

摘要

本研究的目的是测定布鲁氏菌病患者血清中微量元素浓度的变化，包括锌（Zn）和铜（Cu），并将其与健康个体的结果进行比较。本研究纳入了75名受试者，其中60名布鲁氏菌病患者和15名健康个体。使用原子吸收分光光度计测定布鲁氏菌病患者血清中的锌和铜浓度，并与健康个体的浓度进行统计学比较。发现布鲁氏菌病患者的血清铜浓度显著高于健康个体（分别为130.5±24.7、96±8.65μg/dl）（p<0.01）。布鲁氏菌病患者的血清锌浓度低于健康受试者（分别为79.5±13.5和83±5.59μg/dl）（p<0.01）。与健康受试者相比，布鲁氏菌病患者的血清微量元素浓度有显著变化。