Cesur Salih, Cebeci Sevsen Altinay, Kavas Guzin Ozelci, Yilmaz Neziha, Buyukkagnici Demet Iren
Refik Saydam Hygiene Center, Tuberculosis Referance and Research Laboratory, Ankara, Turkey.
J Infect. 2005 Jul;51(1):35-7. doi: 10.1016/j.jinf.2004.08.003.
The aim of this study was to measure the alterations in serum trace elements, including zinc and copper in patients with chronic hepatitis C and to compare them with the results of healthy individuals. Seventeen patients with chronic hepatitis C and 17 healthy individuals were included in this study. Serum zinc and cooper concentrations were measured by using atomic absorption spectrophotometer of patients with chronic hepatitis C and the results were statistically compared with those of healthy individuals. Serum zinc concentrations were 105.6+/-22.8 microg/dl in patients with chronic hepatitis C and 94.41+/-19 microg/dl in healthy controls, respectively. Serum copper concentrations were 103.17+/-20.8 microg/dl in patients with chronic hepatitis C and 90.8+/-14.3 microg/dl in healthy subjects, respectively. Serum zinc and copper concentrations were not found statistically different in patients with chronic hepatitis C compared with those of healthy individuals (p>0.05). In conclusion, serum trace element concentrations did not show statistical alterations in patients with chronic hepatitis C compared to healthy subjects.
本研究的目的是测定慢性丙型肝炎患者血清微量元素（包括锌和铜）的变化，并将其与健康个体的结果进行比较。本研究纳入了17例慢性丙型肝炎患者和17名健康个体。使用原子吸收分光光度计测定慢性丙型肝炎患者的血清锌和铜浓度，并将结果与健康个体的结果进行统计学比较。慢性丙型肝炎患者的血清锌浓度分别为105.6±22.8微克/分升，健康对照者为94.41±19微克/分升。慢性丙型肝炎患者的血清铜浓度分别为103.17±20.8微克/分升，健康受试者为90.8±14.3微克/分升。与健康个体相比，慢性丙型肝炎患者的血清锌和铜浓度未发现统计学差异（p>0.05）。总之，与健康受试者相比，慢性丙型肝炎患者的血清微量元素浓度未显示出统计学变化。
