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慢性丙型肝炎患者的血清铜和锌浓度

Serum copper and zinc concentrations in patients with chronic hepatitis C.

作者信息

Cesur Salih, Cebeci Sevsen Altinay, Kavas Guzin Ozelci, Yilmaz Neziha, Buyukkagnici Demet Iren

机构信息

Refik Saydam Hygiene Center, Tuberculosis Referance and Research Laboratory, Ankara, Turkey.

出版信息

J Infect. 2005 Jul;51(1):35-7. doi: 10.1016/j.jinf.2004.08.003.

Abstract

The aim of this study was to measure the alterations in serum trace elements, including zinc and copper in patients with chronic hepatitis C and to compare them with the results of healthy individuals. Seventeen patients with chronic hepatitis C and 17 healthy individuals were included in this study. Serum zinc and cooper concentrations were measured by using atomic absorption spectrophotometer of patients with chronic hepatitis C and the results were statistically compared with those of healthy individuals. Serum zinc concentrations were 105.6+/-22.8 microg/dl in patients with chronic hepatitis C and 94.41+/-19 microg/dl in healthy controls, respectively. Serum copper concentrations were 103.17+/-20.8 microg/dl in patients with chronic hepatitis C and 90.8+/-14.3 microg/dl in healthy subjects, respectively. Serum zinc and copper concentrations were not found statistically different in patients with chronic hepatitis C compared with those of healthy individuals (p>0.05). In conclusion, serum trace element concentrations did not show statistical alterations in patients with chronic hepatitis C compared to healthy subjects.

摘要

本研究的目的是测定慢性丙型肝炎患者血清微量元素(包括锌和铜)的变化,并将其与健康个体的结果进行比较。本研究纳入了17例慢性丙型肝炎患者和17名健康个体。使用原子吸收分光光度计测定慢性丙型肝炎患者的血清锌和铜浓度,并将结果与健康个体的结果进行统计学比较。慢性丙型肝炎患者的血清锌浓度分别为105.6±22.8微克/分升,健康对照者为94.41±19微克/分升。慢性丙型肝炎患者的血清铜浓度分别为103.17±20.8微克/分升,健康受试者为90.8±14.3微克/分升。与健康个体相比,慢性丙型肝炎患者的血清锌和铜浓度未发现统计学差异(p>0.05)。总之,与健康受试者相比,慢性丙型肝炎患者的血清微量元素浓度未显示出统计学变化。

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