通过连续的VNS(Ar)-S(N)Ar三组分偶联反应合成二芳基乙酸酯和羟吲哚。
Synthesis of diaryl acetates and oxindoles via a sequential VNS(Ar)-S(N)Ar three-component coupling reaction.
作者信息
Lawrence Nicholas J, Davies Christopher A, Gray Matthew
机构信息
Department of Chemistry, Cardiff University, P.O. Box 912, Cardiff, CF10 3TB, UK.
出版信息
Org Lett. 2004 Dec 23;6(26):4957-60. doi: 10.1021/ol047890y.
PMID:15606109
Abstract
[reaction: see text] The VNS and S(N)Ar reactions combine to form an efficient three-component one-pot route to diarylmethanes. The products of selected diaryl acetates provide modular 3-aryloxindole derivatives.
摘要
[反应：见正文] 伏立诺他（VNS）反应和芳香亲核取代反应（S(N)Ar）相结合，形成了一种高效的三组分一锅法合成二芳基甲烷的路线。所选二芳基乙酸酯的产物可提供模块化的3-芳基氧化吲哚衍生物。
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