肉毒杆菌毒素注射治疗足底多汗症和点状掌跖角化病。
Plantar hyperhidrosis and pitted keratolysis treated with botulinum toxin injection.
作者信息
Tamura Bhertha M, Cucé Luiz Carlos, Souza Raquel Leão, Levites Jacob
机构信息
General Hospital of the Medical School of the University of São Paulo, São Paulo, Brazil.
出版信息
Dermatol Surg. 2004 Dec;30(12 Pt 2):1510-4. doi: 10.1111/j.1524-4725.2004.30553.x.
BACKGROUND
Sulcate plantare keratolysis or pitted keratolysis (plantar keratolysis sulcatum) is a disease that is commonly found in tropical countries. Patients have also reported plantar hyperhidrosis.
OBJECTIVE
Two patients with pitted keratolysis resistant to topical and systemic treatments are described.
METHODS
Both patients were injected with botulinum toxin distributed evenly through the plantar extension.
RESULTS
The response to the treatment was excellent despite using a low dose of botulinum toxin with the plantar keratolysis healing completely.
CONCLUSION
Hyperhidrosis may be considered the major etiologic factor for pitted keratolysis that does not respond to treatment.
背景
沟状跖部角质松解症或点状掌跖角皮症（跖沟状角质松解症）是一种在热带国家常见的疾病。患者也有足底多汗症的报告。
目的
描述两名对局部和全身治疗均耐药的点状掌跖角皮症患者。
方法
两名患者均通过足底伸展均匀注射肉毒杆菌毒素。
结果
尽管使用低剂量肉毒杆菌毒素，但治疗反应良好，跖部角质松解症完全愈合。
结论
多汗症可能被认为是对治疗无反应的点状掌跖角皮症的主要病因。
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