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[角化过度型点状掌跖角化病及病原体分离:棒状杆菌属]

[Pitted keratolysis of hyperkeratotic form and isolation of the etiologic agent: Corynebacterium sp].

作者信息

Conti Díaz I A, Cestau de Peluffo I, Civila E, Calegari L, Sanabria D, Viegas M C

机构信息

Departamento de Parasitología, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay.

出版信息

Med Cutan Ibero Lat Am. 1987;15(2):157-60.

PMID:3309502
Abstract

Two cases of "pitted keratolysis" with a very accentuated plantar hyperkeratosis, and the isolation on chocolate thelurite agar of the presumptive etiologic agent, Corynebacterium sp., is presented. In order to keep permanently in mind, for a proper diagnosis, the original description of the disease as "keratoma plantare sulcatum" (Castellani, 1910), we are proposing to distinguish two different clinical forms: The hyperkeratotic one and the common or usual form of "pitted keratolysis" with keratolysis as the main sign. The prosecution of our biochemical studies with a significant number of strains isolated from both "pitted keratolysis" and from classical erythrasma cases, will surely permit us to definitively determine if all of them should or not be assimilated to Corynebacterium minutissimum.

摘要

本文报告了两例“凹坑状角质松解症”,伴有非常明显的足底角化过度,并在巧克力噻吩酮琼脂上分离出推测的病原体棒状杆菌属。为了在正确诊断时永远记住该病最初被描述为“沟状跖角皮瘤”(卡斯特拉尼,1910年),我们建议区分两种不同的临床形式:角化过度型和以角质松解为主要体征的“凹坑状角质松解症”的常见或普通形式。对从“凹坑状角质松解症”和经典红癣病例中分离出的大量菌株进行生化研究,肯定会使我们能够最终确定它们是否都应归为微小棒状杆菌。

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