Hermida Leandro, Brachat Sophie, Voegeli Sylvia, Philippsen Peter, Primig Michael
Department of Applied Microbiology, Biozentrum, Klingelbergstrasse 50-70, CH-4056 Basel, Switzerland.
Nucleic Acids Res. 2005 Jan 1;33(Database issue):D348-52. doi: 10.1093/nar/gki009.
The Ashbya Genome Database (AGD) is a comprehensive online source of information covering genes from the filamentous fungus Ashbya gossypii. The database content is based upon comparative genome annotation between A.gossypii and the closely related budding yeast Saccharomyces cerevisiae taking both sequence similarity and synteny (conserved order and orientation) into account. Release 2 of AGD contains 4718 protein-encoding loci located across seven chromosomes. Information can be retrieved using systematic or standard locus names from A.gossypii as well as budding and fission yeast. Approximately 90% of the genes in the genome of A.gossypii are homologous and syntenic to loci of budding yeast. Therefore, AGD is a useful tool not only for the various yeast communities in general but also for biologists who are interested in evolutionary aspects of genome research and comparative genome annotation. The database provides scientists with a convenient graphical user interface that includes various locus search and genome browsing options, data download and export functionalities and numerous reciprocal links to external databases including SGD, MIPS, GeneDB, KEGG, GermOnline and Swiss-Prot/TrEMBL. AGD is accessible at http://agd.unibas.ch/.
棉阿舒囊霉基因组数据库（AGD）是一个全面的在线信息源，涵盖丝状真菌棉阿舒囊霉的基因。该数据库的内容基于棉阿舒囊霉与亲缘关系密切的芽殖酵母酿酒酵母之间的比较基因组注释，同时考虑了序列相似性和共线性（保守的顺序和方向）。AGD的第2版包含位于7条染色体上的4718个蛋白质编码基因座。可以使用棉阿舒囊霉以及芽殖酵母和裂殖酵母的系统或标准基因座名称来检索信息。棉阿舒囊霉基因组中约90%的基因与芽殖酵母的基因座同源且共线。因此，AGD不仅对一般的各种酵母群体有用，而且对那些对基因组研究的进化方面和比较基因组注释感兴趣的生物学家也有用。该数据库为科学家提供了一个方便的图形用户界面，其中包括各种基因座搜索和基因组浏览选项、数据下载和导出功能以及与包括SGD、MIPS、GeneDB、KEGG、GermOnline和Swiss-Prot/TrEMBL在内的外部数据库的众多相互链接。可通过http://agd.unibas.ch/访问AGD。
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