Ostrowski S, Biłan A
Chair and Department of Medicine, Lublin University School of Medicine, Lublin, Poland.
J Physiol Pharmacol. 2004 Sep;55 Suppl 3:95-100.
Lung growth starts in the first year of life. Between 20-30 years of age, man achieves the maximum FEV1. Some years later, maximum FVC is achieved. After the phase of a dynamic increase, lung function stabilizes for a while. Thereafter, it starts declining slowly in some individuals or increasing in others. The third and last phase of lung function changes during a lifetime begins between 40-45 years of life. The FEV1 and some years later also FVC diminish with a varied speed during this period. Changes in FEV1 and FVC in the third phase are slower at the beginning and accelerate in the six or seventh decade of life. There are some differences between males and females concerning the lung function profile. Female lung function starts decreasing earlier than that in male individuals. There are also pronounced interindividual differences in lung function among individuals of a similar age and body height.
肺的生长始于生命的第一年。在20至30岁之间，男性的第一秒用力呼气容积（FEV1）达到最大值。几年后，用力肺活量（FVC）达到最大值。在动态增长阶段之后，肺功能会稳定一段时间。此后，在一些个体中肺功能开始缓慢下降，而在另一些个体中则继续上升。肺功能在一生中变化的第三个也是最后一个阶段始于40至45岁。在此期间，FEV1以及几年后的FVC会以不同的速度下降。第三阶段FEV1和FVC的变化在开始时较慢，并在六七十岁时加速。在肺功能状况方面，男性和女性之间存在一些差异。女性肺功能比男性更早开始下降。在年龄和身高相似的个体之间，肺功能也存在明显的个体差异。
