Burgos-Vargas R, Petty R E
Rheumatology Unit, Hospital General de México, Mexico City.
Rheum Dis Clin North Am. 1992 Feb;18(1):123-42.
We are beginning to understand the clinical nature of JAS, its relationship with other SSA, and factors involved in its pathogenesis. Clinical data may now allow early recognition of JAS through the identification of children with the SEA syndrome or chronic arthritis associated with the HLA-B27. Comparative clinical studies of the prevalence of the disease and the role of immunogenetic, racial and environmental factors are needed. It may be necessary to review current criteria for the diagnosis of JRA and to develop similar criteria for the diagnosis of AS in childhood and adolescence.
我们开始了解青少年强直性脊柱炎（JAS）的临床特征、它与其他血清阴性脊柱关节病（SSA）的关系以及其发病机制中涉及的因素。目前临床数据或许可通过识别患有SEA综合征或与HLA - B27相关的慢性关节炎的儿童来实现对JAS的早期诊断。需要开展关于该疾病患病率以及免疫遗传学、种族和环境因素作用的比较临床研究。可能有必要重新审视目前幼年特发性关节炎（JRA）的诊断标准，并制定针对儿童和青少年强直性脊柱炎（AS）诊断的类似标准。
