Østergaard Jens, Boberg-Ans Jannik, Prause Jan Ulrik, Heegaard Steffen
Eye Pathology Institute, University of Copenhagen, Frederik V's Vej 11, 2100, Copenhagen, Denmark.
Graefes Arch Clin Exp Ophthalmol. 2005 Jun;243(6):615-8. doi: 10.1007/s00417-004-1086-5. Epub 2004 Dec 22.
To report the clinical and histopathological characteristics of a patient with a primary basal cell carcinoma (BCC) of the caruncle with seeding of the tumour to the conjunctiva.
Surgical excision and histological examination.
A 60-year-old female presented with a lesion of the caruncle. Clinical examination revealed a pale lobulated tumour without skin involvement. Computer tomography scans showed orbital invasion. The tumour was excised. Three years later a small polypoid tumour developed in the inferior fornix of the same eye. Two and a half years later, the patient developed an orbital recurrence. Microscopically, both neoplasms were composed of infiltrative islands of basaloid tumour cells, scattered mitoses and peripheral palisading consistent with the diagnosis of BCC.
This case describes a primary BCC of the caruncle with seeding to the conjunctiva.
报告一例原发于泪阜的基底细胞癌(BCC)并伴有肿瘤播散至结膜的患者的临床及组织病理学特征。
手术切除及组织学检查。
一名60岁女性,泪阜出现肿物。临床检查发现一个苍白的分叶状肿瘤,未累及皮肤。计算机断层扫描显示眼眶受侵。肿瘤被切除。三年后,同一只眼的下穹窿出现一个小的息肉样肿瘤。两年半后,患者出现眼眶复发。显微镜下,两个肿瘤均由基底样肿瘤细胞的浸润性岛状结构、散在的有丝分裂象及周边栅栏状排列组成,符合基底细胞癌的诊断。
本病例描述了一例原发于泪阜的基底细胞癌并伴有向结膜播散。