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内眦原发性基底细胞癌 1 例报告及文献复习

Primary basal cell carcinoma of the caruncle: case report and review of the literature.

机构信息

Instituto Nacional de Oftalmología "Dr. Francisco Contreras Campos", Lima, Perú.

Universidad Peruana Cayetano Heredia, Lima, Perú.

出版信息

Arq Bras Oftalmol. 2024 Mar 22;87(3):e20220357. doi: 10.5935/0004-2749.2022-0357. eCollection 2024.

DOI:10.5935/0004-2749.2022-0357
PMID:38537041
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11627277/
Abstract

We present a rare case of primary caruncle basal cell carcinoma (BCC), a condition with limited occurrences. Our patient, an 80-year-old woman without prior ocular pathological history, presented a 2x2mm pedunculated blackish nodular lesion on the caruncle of her left eye, without local conjunctival or cutaneous involvement. Histological analysis following complete excision confirmed the presence of basal cell carcinoma within the caruncle. Over a span of 30 months, no recurrence has been observed. While scant cases are documented in the literature, we conducted a review of these instances. Despite its infrequent manifestation, this condition should be taken into account when evaluating caruncular tumors, given its tendency to invade the orbit. Complete excision with free surgical margins is the treatment of choice, and adjuvant radiotherapy or chemotherapy might be considered.

摘要

我们报告了一例罕见的原发性穹隆基底细胞癌(BCC),这种情况的发生率有限。我们的患者是一位 80 岁的女性,没有眼部病理病史,左眼穹隆部出现一个 2x2mm 的带蒂黑褐色结节状病变,无局部结膜或皮肤受累。完全切除后的组织学分析证实了穹隆部存在基底细胞癌。在 30 个月的时间里,没有观察到复发。尽管文献中有少量病例报道,但我们对这些病例进行了回顾。尽管这种情况很少见,但在评估穹隆部肿瘤时应考虑到这种情况,因为它有侵犯眼眶的倾向。彻底切除并游离手术边缘是首选的治疗方法,辅助放疗或化疗可能是需要考虑的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7ad/11627277/1aebdff0bdac/abo-87-03-e20220357-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7ad/11627277/0089f219bb25/abo-87-03-e20220357-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7ad/11627277/b970a1fe7f2c/abo-87-03-e20220357-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7ad/11627277/1aebdff0bdac/abo-87-03-e20220357-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7ad/11627277/0089f219bb25/abo-87-03-e20220357-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7ad/11627277/b970a1fe7f2c/abo-87-03-e20220357-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7ad/11627277/1aebdff0bdac/abo-87-03-e20220357-g03.jpg

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本文引用的文献

1
[Primary basal cell carcinoma of the caruncle].[泪阜原发性基底细胞癌]
Ophthalmologe. 2019 Nov;116(11):1034-1037. doi: 10.1007/s00347-019-0895-1.
2
Basal Cell Carcinoma Review.基底细胞癌综述。
Hematol Oncol Clin North Am. 2019 Feb;33(1):13-24. doi: 10.1016/j.hoc.2018.09.004.
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Histologic Mimics of Basal Cell Carcinoma.基底细胞癌的组织学模仿物
Arch Pathol Lab Med. 2017 Nov;141(11):1490-1502. doi: 10.5858/arpa.2017-0222-RA.
4
Conjunctival Tumors in 5002 Cases. Comparative Analysis of Benign Versus Malignant Counterparts. The 2016 James D. Allen Lecture.5002例结膜肿瘤。良性与恶性对应物的比较分析。2016年詹姆斯·D·艾伦讲座
Am J Ophthalmol. 2017 Jan;173:106-133. doi: 10.1016/j.ajo.2016.09.034. Epub 2016 Oct 8.
5
Primary basal cell carcinoma of the caruncle: case report and review of the literature.摘要: 本文报告了一例原发性内眦部基底细胞癌,并对相关文献进行了回顾。
Ophthalmic Plast Reconstr Surg. 2014 May-Jun;30(3):e62-4. doi: 10.1097/IOP.0b013e31829bb48c.
6
First reported case of primary basal cell carcinoma of the right caruncle: a case report and review of the literature.右穹窿部原发性基底细胞癌 1 例报告及文献复习
In Vivo. 2013 Jul-Aug;27(4):535-9.
7
Primary ocular caruncular basal cell carcinoma in a Chinese patient.中国患者原发性眼附属器基底细胞癌。
Kaohsiung J Med Sci. 2010 Oct;26(10):562-6. doi: 10.1016/S1607-551X(10)70087-5.
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Lesions of the caruncle: a description of 42 cases and a review of the literature.眼阜病变:42 例描述及文献复习。
Eye (Lond). 2009 May;23(5):1004-18. doi: 10.1038/eye.2008.316. Epub 2008 Oct 17.
9
Tumors of the caruncle: a clinicopathologic correlation.泪阜肿瘤:临床病理相关性
Am J Ophthalmol. 2006 Sep;142(3):448-55. doi: 10.1016/j.ajo.2006.04.035.
10
Basal cell carcinoma of the caruncle.泪阜基底细胞癌
Ophthalmic Plast Reconstr Surg. 2006 Jul-Aug;22(4):313-4. doi: 10.1097/01.iop.0000226921.48952.92.