喀麦隆产CTX-M-15肠杆菌的出现及携带blaCTX-M-15元件的特征分析
Emergence of CTX-M-15-producing enterobacteria in Cameroon and characterization of a blaCTX-M-15-carrying element.
作者信息
Gangoue-Pieboji J, Miriagou V, Vourli S, Tzelepi E, Ngassam P, Tzouvelekis L S
机构信息
Laboratory of Bacteriology, Hellenic Pasteur Institute, Vas. Sofias 127, Athens 11521, Greece.
出版信息
Antimicrob Agents Chemother. 2005 Jan;49(1):441-3. doi: 10.1128/AAC.49.1.441-443.2005.
Abstract
CTX-M-15-producing Klebsiella pneumoniae and Escherichia coli emerged recently in Cameroon. CTX-M-15 was encoded by two different multiresistance plasmids, of which one carried an ISEcp1-bla(CTX-M-15) element flanked by a 5-bp target site duplication and inserted within a Tn2-derived sequence. A truncated form of this element in the second plasmid was identified.
摘要
产CTX-M-15的肺炎克雷伯菌和大肠杆菌最近在喀麦隆出现。CTX-M-15由两种不同的多耐药性质粒编码，其中一种携带一个ISEcp1-bla(CTX-M-15)元件，两侧有一个5碱基对的靶位点重复序列，并插入到一个Tn2衍生序列中。在第二个质粒中鉴定出了该元件的截短形式。
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