Svoboda P, Ochmann J, Sefr R, Kantorová I
Výzkumný ústav traumatologie a speciální chirurgie, Brno.
Vnitr Lek. 1992 Jan;38(1):49-55.
The authors submit the results of 1061 endoscopic sclerotizations of oesophageal varices in 183 patients. For sclerotization they used endoscopes of Olympus Co. at two-week intervals. Treatment was supplemented by administration of drugs reducing portal pressure. The number of complications associated with this treatment is very low. Serious life-threatening complications occur in much less than 1%. The authors consider endoscopic sclerotization of oesophageal varices after the first haemorrhage as the method of choice, in particular in combination with medicamentous treatment for reduction of portal pressure. They emphasize the necessity to perform these procedures in a department with adequate experience with sclerotizations where at least 100-200 sclerotization per year are performed. In the discussion other therapeutic possibilities are suggested. The problem of preventive sclerotization of varices has not been resolved so far. The authors recommend it in their department and use it in patients who according to the endoscopic finding or the level of the portocaval gradient are at risk of haemorrhage.
作者提交了183例患者1061次食管静脉曲张内镜硬化治疗的结果。硬化治疗使用奥林巴斯公司的内镜,每隔两周进行一次。治疗辅以使用降低门静脉压力的药物。该治疗相关的并发症数量非常低。严重危及生命的并发症发生率远低于1%。作者认为首次出血后食管静脉曲张内镜硬化治疗是首选方法,特别是与降低门静脉压力的药物治疗联合使用时。他们强调必须在有足够硬化治疗经验的科室进行这些操作,每年至少进行100 - 200次硬化治疗。在讨论中还提出了其他治疗可能性。静脉曲张的预防性硬化治疗问题至今尚未解决。作者在其科室推荐并用于根据内镜检查结果或门腔静脉梯度水平有出血风险的患者。