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翅茎西番莲茶的化学研究及其对大鼠生化参数的影响。

Chemical investigation and effects of the tea of Passiflora alata on biochemical parameters in rats.

作者信息

Doyama J T, Rodrigues H G, Novelli E L B, Cereda E, Vilegas W

机构信息

Departamento de Química e Bioquímica, Instituto de Biociências, UNESP, Botucatu SP, CEP 18618-000, Brazil.

出版信息

J Ethnopharmacol. 2005 Jan 15;96(3):371-4. doi: 10.1016/j.jep.2004.06.021. Epub 2004 Dec 2.

DOI:10.1016/j.jep.2004.06.021
PMID:15619554
Abstract

Passiflora alata (Passifloraceae) is a native plant from the South-America tropical forest that provides a much appreciated fruit known as "maracujá-doce". Although tea of the leaves of Passiflora alata is used in folk medicine as a sedative and tranquilizer, there are no investigations about its effects on biochemical parameters in blood or from its major chemical composition. The purpose of this study was to evaluate the effects of the tea of the leaves of Passiflora alata on biochemical parameters (antioxidant system, glucose and cholesterol levels) and to perform a phytochemical investigation of the tea. We isolated and identified two saponins and five C-glycosylflavones derived from apigenin, luteolin and chrysoeriol. Three of them are new in this species. Passiflora alata extract was administrated orally in rats at dose of 1000 mg/kg and it was observed an increase in high-density lipoprotein level (HDL-cholesterol).

摘要

翅茎西番莲(西番莲科)是一种原产于南美洲热带森林的植物,其果实“甜西番莲”备受喜爱。尽管翅茎西番莲的叶茶在民间医学中用作镇静剂和 tranquilizer,但尚无关于其对血液生化参数或主要化学成分影响的研究。本研究的目的是评估翅茎西番莲叶茶对生化参数(抗氧化系统、血糖和胆固醇水平)的影响,并对该叶茶进行植物化学研究。我们分离并鉴定了两种皂苷和五种源自芹菜素、木犀草素和 Chrysoeriol 的 C-糖基黄酮。其中三种在该物种中是新发现的。以 1000 mg/kg 的剂量给大鼠口服翅茎西番莲提取物,观察到高密度脂蛋白水平(HDL-胆固醇)升高。 注:原文中tranquilizer未翻译,因为它可能是一个特定医学术语,未找到准确中文对应,保留英文更合适。

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