Kunming Institute of Botany, Chinese Academy of Sciences, Kunming , People's Republic of China.
Food Chem. 2013 Jan 1;136(1):94-9. doi: 10.1016/j.foodchem.2012.07.101. Epub 2012 Aug 4.
The stems and leaves of Passiflora edulis Sims, are used as a folk medicine for treating both anxiety and nervousness in American countries. Phytochemical investigation of the n-butanol (n-BuOH) fraction of this plant led to the isolation of four new 2,6-dideoxyhexose-C-glycosyl flavones, including luteolin-8-C-β-digitoxopyranosyl-4'-O-β-d-glucopyranoside (1), apigenin-8-C-β-digitoxopyranoside (2), apigenin-8-C-β-boivinopyranoside (3) and luteolin-8-C-β-boivinopyranoside (4), together with five known compounds (5-9). The structures of these compounds were elucidated by extensive spectroscopic methods. All compounds were evaluated for their neurite outgrowth enhancing activities and the results indicated that luteolin (7) enhanced NGF-induced neurite outgrowth in PC12 cells at 50.0μM.
西番莲的茎叶被用作治疗焦虑和紧张的民间药物，在美国和其他国家。植物化学研究表明，这种植物的正丁醇（n-BuOH）部分分离得到了四种新的 2,6-去氧己糖-C-糖苷黄酮，包括木樨草素-8-C-β-毛地黄糖苷-4'-O-β-D-吡喃葡萄糖苷（1）、芹菜素-8-C-β-毛地黄糖苷（2）、芹菜素-8-C-β-波伊文糖苷（3）和木樨草素-8-C-β-波伊文糖苷（4），以及五种已知化合物（5-9）。这些化合物的结构通过广泛的光谱方法阐明。所有化合物均进行了促进神经突生长活性的评价，结果表明木樨草素（7）在 50.0μM 时增强了 NGF 诱导的 PC12 细胞的神经突生长。
